3MJK

Structure of a growth factor precursor

Summary for 3MJK

• Entry DOI: 10.2210/pdb3mjk/pdb
• Descriptor: Platelet-derived growth factor subunit A (2 entities in total)
• Functional Keywords: cystine-knot, growth factor, hormone
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P04085
• Total number of polymer chains: 6
• Total formula weight: 116402.26

Authors

Liu, H.,He, X. (deposition date: 2010-04-12, release date: 2010-06-16, Last modification date: 2023-09-06)

• Primary citation: Shim, A.H.,Liu, H.,Focia, P.J.,Chen, X.,Lin, P.C.,He, X.; Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex.; Proc.Natl.Acad.Sci.USA, 107:11307-11312, 2010; PubMed: 20534510; DOI: 10.1073/pnas.1000806107

Experimental method

X-RAY DIFFRACTION (2.4 Å)