5T89

Crystal structure of VEGF-A in complex with VEGFR-1 domains D1-6

Summary for 5T89

DescriptorVascular endothelial growth factor A, Vascular endothelial growth factor receptor 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywordsreceptor tyrosine kinase, growth factor, immunoglobulin domain, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains4
Total molecular weight182190.52
Authors
Markovic-Mueller, S.,Stuttfeld, E.,Asthana, M.,Weinert, T.,Bliven, S.,Goldie, K.N.,Kisko, K.,Capitani, G.,Ballmer-Hofer, K. (deposition date: 2016-09-07, release date: 2017-02-01, Last modification date: 2020-07-29)
Primary citation
Markovic-Mueller, S.,Stuttfeld, E.,Asthana, M.,Weinert, T.,Bliven, S.,Goldie, K.N.,Kisko, K.,Capitani, G.,Ballmer-Hofer, K.
Structure of the Full-length VEGFR-1 Extracellular Domain in Complex with VEGF-A.
Structure, 25:341-352, 2017
PubMed: 28111021 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2016.12.012
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.31813 2.6% 6.0% 0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
169117
PDB entries from 2020-09-23