6BFT

Structure of Bevacizumab Fab mutant in complex with VEGF

Summary for 6BFT

• Entry DOI: 10.2210/pdb6bft/pdb
• Related: 6ARP 6ARU
• Descriptor: Avastin Light Chain Fab fragment mutant, Avastin Heavy Chain Fab fragment mutant, Vascular endothelial growth factor A, ... (6 entities in total)
• Functional Keywords: avastin, antibody, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 121343.33

Authors

Christie, M.,Christ, D. (deposition date: 2017-10-27, release date: 2018-10-31, Last modification date: 2024-10-16)

• Primary citation: Christie, M.,Rouet, R.,Nevoltris, D.,Langley, D.,Schofield, P.,Fabri, L.,Tingey, K.,Lowe, D.,Jermutus, L.,Christ, D.; Stable human IgG antibody therapeutics with native framework structure; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.55 Å)