7YQ6
 
 | | human insulin receptor bound with A62 DNA aptamer | | 分子名称: | IR-A62 aptamer, Isoform Short of Insulin receptor | | 著者 | Kim, J, Yunn, N, Ryu, S, Cho, Y. | | 登録日 | 2022-08-05 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.18 Å) | | 主引用文献 | Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures.
Nat Commun, 13, 2022
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7YQ5
 | | human insulin receptor bound with A62 DNA aptamer and insulin | | 分子名称: | IR-A62 aptamer, Insulin A chain, Insulin, ... | | 著者 | Kim, J, Yunn, N, Ryu, S, Cho, Y. | | 登録日 | 2022-08-05 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.27 Å) | | 主引用文献 | Functional selectivity of insulin receptor revealed by aptamer-trapped receptor structures.
Nat Commun, 13, 2022
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8DTM
 | | Cryo-EM structure of insulin receptor (IR) bound with S597 component 2 | | 分子名称: | Insulin mimetic peptide S597 component 2, Insulin receptor | | 著者 | Park, J, Li, J, Mayer, J.P, Ball, K.A, Wu, J.Y, Hall, C, Accili, D, Stowell, M.H.B, Bai, X.C, Choi, E. | | 登録日 | 2022-07-26 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-10-12 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Activation of the insulin receptor by an insulin mimetic peptide.
Nat Commun, 13, 2022
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8DTL
 | | Cryo-EM structure of insulin receptor (IR) bound with S597 peptide | | 分子名称: | Insulin mimetic peptide S597, Insulin receptor | | 著者 | Park, J, Li, J, Mayer, J.P, Ball, K.A, Wu, J.Y, Hall, C, Accili, D, Stowell, M.H.B, Bai, X.C, Choi, E. | | 登録日 | 2022-07-25 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-10-12 | | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | | 主引用文献 | Activation of the insulin receptor by an insulin mimetic peptide.
Nat Commun, 13, 2022
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8AFP
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8AFO
 | | Structure of fibronectin 2 and 3 of L1CAM at 2.0 Angstrom | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neural cell adhesion molecule L1 | | 著者 | Guedez, G, Loew, C. | | 登録日 | 2022-07-18 | | 公開日 | 2023-03-08 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | X-ray structure and function of fibronectin domains two and three of the neural cell adhesion molecule L1.
Faseb J., 37, 2023
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8DPU
 | | The crystal structure of the IL-11 signalling complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ... | | 著者 | Metcalfe, R.D, Aizel, K, Griffin, M.D.W. | | 登録日 | 2022-07-17 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.78 Å) | | 主引用文献 | Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant.
Nat Commun, 14, 2023
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8DPS
 | | The structure of the interleukin 11 signalling complex, truncated gp130 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ... | | 著者 | Metcalfe, R.D, Hanssen, E, Griffin, M.D.W. | | 登録日 | 2022-07-17 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant.
Nat Commun, 14, 2023
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8DPT
 | | The structure of the IL-11 signalling complex, with full-length extracellular gp130 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ... | | 著者 | Metcalfe, R.D, Hanssen, E, Griffin, M.D.W. | | 登録日 | 2022-07-17 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant.
Nat Commun, 14, 2023
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8DH8
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7Y8S
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7Y8I
 | | Crystal structure of sDscam FNIII3 domain, isoform alpha7 | | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Dscam, ... | | 著者 | Chen, Q, Yu, Y, Cheng, J. | | 登録日 | 2022-06-24 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for the self-recognition of sDSCAM in Chelicerata.
Nat Commun, 14, 2023
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7Y8H
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7Y6E
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7Y5R
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8D74
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8D7R
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8D7E
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8D7H
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8D82
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8D85
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8D6A
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8A16
 | | Human PTPRM domains FN3-4, in spacegroup P212121 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase mu, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Caroe, E, Graham, S.C, Sharpe, H.J, Deane, J.E. | | 登録日 | 2022-05-31 | | 公開日 | 2023-03-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains.
J.Biol.Chem., 299, 2023
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8A17
 | | Human PTPRM domains FN3-4, in spacegroup P3221 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase mu, ... | | 著者 | Shamin, M, Graham, S.C, Sharpe, H.J, Deane, J.E. | | 登録日 | 2022-05-31 | | 公開日 | 2023-03-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | | 主引用文献 | Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains.
J.Biol.Chem., 299, 2023
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7ZXK
 | | Human IL-27 in complex with neutralizing SRF388 FAb fragment | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 subunit alpha, Interleukin-27 subunit beta, ... | | 著者 | Bloch, Y, Skladanowska, K, Strand, J, Welin, M, Logan, D, Hill, J, Savvides, S.N. | | 登録日 | 2022-05-21 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27.
Cell Rep, 41, 2022
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