PDB: 1507 件ウェブページステータス検索Chemie searchBIRD

---

5V1Z	Crystal structure of the RPN13 PRU-RPN2 (932-953)-ubiquitin complex 分子名称: 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1, Ubiquitin 著者 Hemmis, C.W, VanderLinden, R.T, Yao, T, Robinson, H, Hill, C.P. 登録日 2017-03-02 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and energetics of pairwise interactions between proteasome subunits RPN2, RPN13, and ubiquitin clarify a substrate recruitment mechanism. J. Biol. Chem., 292, 2017
9BOL	Crystal structure of the complex between VHL, ElonginB, ElonginC, and compound 5 分子名称: (4R)-1-[(2S)-2-(4-cyclopropyl-1H-1,2,3-triazol-1-yl)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}-L-prolinamide, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Murray, J.M, Wu, H, Fuhrmann, J, Fairbrother, W.J, DiPasquale, A. 登録日 2024-05-03 公開日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Potency-enhanced peptidomimetic VHL ligands with improved oral bioavailability To Be Published
6QML	UCHL3 in complex with synthetic, K27-linked diubiquitin 分子名称: 1,2-ETHANEDIOL, BROMIDE ION, CHLORIDE ION, ... 著者 Murachelli, A.G, Sixma, T.K. 登録日 2019-02-07 公開日 2020-02-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 K27-Linked Diubiquitin Inhibits UCHL3 via an Unusual Kinetic Trap. Cell Chem Biol, 28, 2021
6R7F	Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome 分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... 著者 Faull, S.V, Lau, A.M.C, Martens, C, Ahdash, Z, Yebenes, H, Schmidt, C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A. 登録日 2019-03-28 公開日 2019-08-28 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (8.2 Å) 主引用文献 Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun, 10, 2019
6R7H	Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome 分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... 著者 Faull, S.V, Lau, A.M.C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A. 登録日 2019-03-28 公開日 2019-08-28 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (8.8 Å) 主引用文献 Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun, 10, 2019
6R7N	Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome 分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... 著者 Faull, S.V, Lau, A.M.C, Martens, C, Ahdash, Z, Yebenes, H, Schmidt, C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A. 登録日 2019-03-29 公開日 2019-08-28 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (6.5 Å) 主引用文献 Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun, 10, 2019
3I3T	Crystal structure of covalent ubiquitin-USP21 complex 分子名称: ETHANAMINE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 21, ... 著者 Neculai, D, Avvakumov, G.V, Walker, J.R, Xue, S, Butler-Cole, C, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2009-06-30 公開日 2009-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 A strategy for modulation of enzymes in the ubiquitin system. Science, 339, 2013
6RPQ	Crystal structure of PhoCDC21-1 intein 分子名称: Ubiquitin-like protein SMT3,1108aa long hypothetical cell division control protein 著者 Beyer, H.M, Mikula, K.M, Iwai, H. 登録日 2019-05-14 公開日 2019-08-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.654 Å) 主引用文献 Crystal structures of CDC21-1 inteins from hyperthermophilic archaea reveal the selection mechanism for the highly conserved homing endonuclease insertion site. Extremophiles, 23, 2019
3IHP	Covalent Ubiquitin-Usp5 Complex 分子名称: CHLORIDE ION, ETHANAMINE, Ubiquitin, ... 著者 Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2009-07-30 公開日 2009-12-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Covalent Ubiquitin-Usp5 Complex To be Published
3IFW	Crystal structure of the S18Y variant of ubiquitin carboxy terminal hydrolase L1 bound to ubiquitin vinylmethylester. 分子名称: METHYL 4-AMINOBUTANOATE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase isozyme L1 著者 Das, C, Boudreaux, D, Maiti, T. 登録日 2009-07-26 公開日 2010-06-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation. Proc.Natl.Acad.Sci.USA, 107, 2010
6SIS	Crystal structure of macrocyclic PROTAC 1 in complex with the second bromodomain of human Brd4 and pVHL:ElonginC:ElonginB 分子名称: Bromodomain-containing protein 4, Elongin-B, Elongin-C, ... 著者 Hughes, S.J, Testa, A, Ciulli, A. 登録日 2019-08-10 公開日 2019-12-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structure-Based Design of a Macrocyclic PROTAC. Angew.Chem.Int.Ed.Engl., 59, 2020
6ML1	Structure of the USP15 deubiquitinase domain in complex with an affinity-matured inhibitory Ubv 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Singer, A.U, Teyra, J, Boehmelt, G, Lenter, M, Sicheri, F, Sidhu, S.S. 登録日 2018-09-26 公開日 2019-01-23 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure, 27, 2019
6MUN	Structure of hRpn10 bound to UBQLN2 UBL 分子名称: 26S proteasome non-ATPase regulatory subunit 4, Ubiquilin-2 著者 Chen, X, Walters, K.J. 登録日 2018-10-23 公開日 2019-09-04 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structure of hRpn10 Bound to UBQLN2 UBL Illustrates Basis for Complementarity between Shuttle Factors and Substrates at the Proteasome. J.Mol.Biol., 431, 2019
6R7I	Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome 分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... 著者 Faull, S.F, Lau, A.M.C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A. 登録日 2019-03-28 公開日 2019-08-28 最終更新日 2019-09-04 実験手法 ELECTRON MICROSCOPY (5.9 Å) 主引用文献 Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun, 10, 2019
6R6H	Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome 分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... 著者 Morris, E.P, Faull, S.V, Lau, A.M.C, Politis, A, Beuron, F, Cronin, N. 登録日 2019-03-27 公開日 2019-08-28 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (8.4 Å) 主引用文献 Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun, 10, 2019
6N5M	Crystal structure of ABIN-1 UBAN in complex with one M1-linked di-ubiquitin 分子名称: Polyubiquitin-C, TNFAIP3-interacting protein 1 著者 Rahighi, S, Dikic, I, Wakatsuki, S. 登録日 2018-11-22 公開日 2019-07-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Molecular Recognition of M1-Linked Ubiquitin Chains by Native and Phosphorylated UBAN Domains. J.Mol.Biol., 431, 2019
6N6R	Crystal structure of ABIN-1 UBAN in complex with two M1-linked di-ubiquitins 分子名称: TNFAIP3-interacting protein 1, Ubiquitin 著者 Rahighi, S, Dikic, I, Wakatsuki, S. 登録日 2018-11-27 公開日 2019-07-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Molecular Recognition of M1-Linked Ubiquitin Chains by Native and Phosphorylated UBAN Domains. J.Mol.Biol., 431, 2019
6RYA	Structure of Dup1 mutant H67A:Ubiquitin complex 分子名称: Polyubiquitin-C, Septation initiation protein 著者 Donghyuk, S, Ivan, D. 登録日 2019-06-10 公開日 2019-11-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Regulation of Phosphoribosyl-Linked Serine Ubiquitination by Deubiquitinases DupA and DupB. Mol.Cell, 77, 2020
3KVF	Crystal structure of the I93M mutant of ubiquitin carboxy terminal hydrolase L1 bound to ubiquitin vinylmethylester 分子名称: METHYL 4-AMINOBUTANOATE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase isozyme L1 著者 Davies, C.W, Maiti, T.K, Das, C. 登録日 2009-11-30 公開日 2010-06-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation. Proc.Natl.Acad.Sci.USA, 107, 2010
3KW5	Crystal structure of ubiquitin carboxy terminal hydrolase L1 bound to ubiquitin vinylmethylester 分子名称: METHYL 4-AMINOBUTANOATE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase isozyme L1 著者 Maiti, T.K, Boudreaux, D.A, Das, C. 登録日 2009-11-30 公開日 2010-06-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation. Proc.Natl.Acad.Sci.USA, 107, 2010
3JSV	Crystal structure of mouse NEMO CoZi in complex with Lys63-linked di-ubiquitin 分子名称: NF-kappa-B essential modulator, Ubiquitin 著者 Yoshikawa, A, Sato, Y, Mimura, H, Yamashita, M, Yamagata, A, Fukai, S. 登録日 2009-09-11 公開日 2009-10-27 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of the NEMO ubiquitin-binding domain in complex with Lys 63-linked di-ubiquitin Febs Lett., 583, 2009
6NJG	Ubiquitin Variant in Complex with Ubiquitin Interacting Motif 分子名称: Polyubiquitin-B, Vacuolar protein sorting-associated protein 27 著者 Manczyk, N, Sicheri, F. 登録日 2019-01-03 公開日 2019-03-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Dimerization of a ubiquitin variant leads to high affinity interactions with a ubiquitin interacting motif. Protein Sci., 28, 2019
6TBM	Structure of SAGA bound to TBP, including Spt8 and DUB 分子名称: Polyubiquitin-B, SAGA-associated factor 11, Spt20, ... 著者 Papai, G, Frechard, A, Kolesnikova, O, Crucifix, C, Schultz, P, Ben-Shem, A. 登録日 2019-11-01 公開日 2020-02-12 最終更新日 2021-06-30 実験手法 ELECTRON MICROSCOPY (20 Å) 主引用文献 Structure of SAGA and mechanism of TBP deposition on gene promoters. Nature, 577, 2020
3L0W	Structure of split monoubiquitinated PCNA with ubiquitin in position two 分子名称: Monoubiquitinated Proliferating cell nuclear antigen, Proliferating cell nuclear antigen 著者 Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T. 登録日 2009-12-10 公開日 2010-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange. Nat.Struct.Mol.Biol., 17, 2010
3L10	Structure of split monoubiquitinated PCNA with ubiquitin in position one 分子名称: Monoubiquitinated Proliferating cell nuclear antigen, Proliferating cell nuclear antigen 著者 Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T. 登録日 2009-12-10 公開日 2010-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange. Nat.Struct.Mol.Biol., 17, 2010

<16171819202122232425262728293031>