9BOL

Crystal structure of the complex between VHL, ElonginB, ElonginC, and compound 5

This is a non-PDB format compatible entry.

Summary for 9BOL

• Entry DOI: 10.2210/pdb9bol/pdb
• Related: 9BJU
• Descriptor: Elongin-B, Elongin-C, von Hippel-Lindau disease tumor suppressor, ... (8 entities in total)
• Functional Keywords: vhl, degradation, degrader, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 87795.04

Authors

Murray, J.M.,Wu, H.,Fuhrmann, J.,Fairbrother, W.J.,DiPasquale, A. (deposition date: 2024-05-03, release date: 2024-05-29)

• Primary citation: Wu, H.,Murray, J.M.,Ishisoko, N.,Frommlet, A.,Fairbrother, W.J.,Fuhrmann, J.; Potency-enhanced peptidomimetic VHL ligands with improved oral bioavailability; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.99 Å)