PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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5VH4	Crystal structure of Fab fragment of anti-TNFa antibody infliximab in an I-centered orthorhombic crystal form 分子名称: 1,2-ETHANEDIOL, Infliximab Fab Heavy Chain, Infliximab Fab Light Chain, ... 著者 Mayclin, S.J, Edwards, T.E, Lerch, T.F, Conlan, H, Sharpe, P. 登録日 2017-04-12 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Infliximab crystal structures reveal insights into self-association. MAbs, 9, 2017
7Y58	CryoEM structure of QacA (D411N), an antibacterial efflux transporter from Staphylococcus aureus 分子名称: Antiseptic resistance protein, Single-domain Indian camelid antibody (A4), single-domain indian camelid antibody(B7) 著者 Penmatsa, A, Majumder, P. 登録日 2022-06-16 公開日 2023-07-12 最終更新日 2023-11-22 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM structure of antibacterial efflux transporter QacA from Staphylococcus aureus reveals a novel extracellular loop with allosteric role. Embo J., 42, 2023
5MI0	A thermally stabilised version of Plasmodium falciparum RH5 分子名称: MONOCLONAL ANTIBODY 9AD4, Reticulocyte binding-like protein 5,Reticulocyte binding protein 5 著者 Campeotto, I, Goldenzweig, A, Davey, J, Barfod, L, Marshall, J.M, Silk, S.E, Wright, K.E, Draper, S.J, Higgins, M.K, Fleishman, S.J. 登録日 2016-11-27 公開日 2016-12-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 One-step design of a stable variant of the malaria invasion protein RH5 for use as a vaccine immunogen. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4LDO	Structure of beta2 adrenoceptor bound to adrenaline and an engineered nanobody 分子名称: (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate, Camelid Antibody Fragment, L-EPINEPHRINE, ... 著者 Ring, A.M, Manglik, A, Kruse, A.C, Enos, M.D, Weis, W.I, Garcia, K.C, Kobilka, B.K. 登録日 2013-06-24 公開日 2013-09-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Adrenaline-activated structure of beta 2-adrenoceptor stabilized by an engineered nanobody. Nature, 502, 2013
4LDE	Structure of beta2 adrenoceptor bound to BI167107 and an engineered nanobody 分子名称: (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate, 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, Camelid Antibody Fragment, ... 著者 Ring, A.M, Manglik, A, Kruse, A.C, Enos, M.D, Weis, W.I, Garcia, K.C, Kobilka, B.K. 登録日 2013-06-24 公開日 2013-09-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Adrenaline-activated structure of beta 2-adrenoceptor stabilized by an engineered nanobody. Nature, 502, 2013
4LDL	Structure of beta2 adrenoceptor bound to hydroxybenzylisoproterenol and an engineered nanobody 分子名称: (2S)-2,3-dihydroxypropyl (7Z)-tetradec-7-enoate, 4-[(1R)-1-hydroxy-2-{[1-(4-hydroxyphenyl)-2-methylpropan-2-yl]amino}ethyl]benzene-1,2-diol, Camelid Antibody Fragment, ... 著者 Ring, A.M, Manglik, A, Kruse, A.C, Enos, M.D, Weis, W.I, Garcia, K.C, Kobilka, B.K. 登録日 2013-06-24 公開日 2013-09-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Adrenaline-activated structure of beta 2-adrenoceptor stabilized by an engineered nanobody. Nature, 502, 2013
5VH3	Crystal structure of Fab fragment of the anti-TNFa antibody infliximab in a C-centered orthorhombic crystal form 分子名称: 1,2-ETHANEDIOL, Infliximab Fab Heavy Chain, Infliximab Fab Light Chain 著者 Mayclin, S.J, Edwards, T.E, Lerch, T.F, Conlan, H, Sharpe, P. 登録日 2017-04-12 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Infliximab crystal structures reveal insights into self-association. MAbs, 9, 2017
5VH5	Crystal Structure of Fc fragment of anti-TNFa antibody infliximab 分子名称: ACETATE ION, Infliximab Fc, ZINC ION, ... 著者 Mayclin, S.J, Edwards, T.E, Lerch, T.F, Conlan, H, Sharpe, P. 登録日 2017-04-12 公開日 2017-05-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Infliximab crystal structures reveal insights into self-association. MAbs, 9, 2017
6FE4	Crystal structure of the complex between Shiga toxin Stx2 B subunit and neutralising Nb113 分子名称: Nb113, Shiga-like toxin 2 subunit B 著者 Bernedo, R, Muyldermans, S, Sterckx, Y.G.J. 登録日 2017-12-29 公開日 2018-03-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural Basis for the Specific Neutralization of Stx2a with a Camelid Single Domain Antibody Fragment. Toxins (Basel), 10, 2018
4MWF	Structure of Hepatitis C Virus Envelope Glycoprotein E2 core bound to broadly neutralizing antibody AR3C 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ... 著者 Kong, L, Wilson, I.A, Law, M. 登録日 2013-09-24 公開日 2013-12-11 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.645 Å) 主引用文献 Hepatitis C virus e2 envelope glycoprotein core structure. Science, 342, 2013
7MMO	LY-CoV1404 neutralizing antibody against SARS-CoV-2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LY-CoV1404 Fab heavy chain, LY-CoV1404 Fab light chain, ... 著者 Hendle, J, Pustilnik, A, Sauder, J.M, Coleman, K.A, Boyles, J.S, Dickinson, C.D. 登録日 2021-04-30 公開日 2021-05-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.427 Å) 主引用文献 LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants. Biorxiv, 2022
6FAB	THREE-DIMENSIONAL STRUCTURE OF MURINE ANTI-P-AZOPHENYLARSONATE FAB 36-71. 1. X-RAY CRYSTALLOGRAPHY, SITE-DIRECTED MUTAGENESIS, AND MODELING OF THE COMPLEX WITH HAPTEN 分子名称: IGG1-KAPPA 36-71 FAB (HEAVY CHAIN), IGG1-KAPPA 36-71 FAB (LIGHT CHAIN) 著者 Strong, R.K, Rose, D.R, Petsko, G.A, Sharon, J, Margolies, M.N. 登録日 1991-01-17 公開日 1993-01-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Three-dimensional structure of murine anti-p-azophenylarsonate Fab 36-71. 1. X-ray crystallography, site-directed mutagenesis, and modeling of the complex with hapten. Biochemistry, 30, 1991
6V80	Crystal structure of human CD1d presenting alpha-Galactosylceramide in complex with NKT12 TCR and VHH nanobody 1D12 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ... 著者 Shahine, A, Rossjohn, J. 登録日 2019-12-10 公開日 2020-09-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.53 Å) 主引用文献 A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response. Nat Cancer, 2020
7JW0	SARS-CoV-2 spike in complex with the S304 neutralizing antibody Fab fragment 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S304 Fab heavy chain, ... 著者 Walls, A.C, Park, Y.J, Tortorici, M.A, Czudnochowski, N, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G, Veesler, D. 登録日 2020-08-24 公開日 2020-10-14 最終更新日 2021-01-27 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology. Cell, 183, 2020
6V7Y	Human CD1d presenting alpha-Galactosylceramide in complex with VHH nanobody 1D5 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ... 著者 Shahine, A, Rossjohn, J. 登録日 2019-12-10 公開日 2020-09-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response. Nat Cancer, 2020
6V7Z	Human CD1d presenting alpha-Galactosylceramide in complex with VHH nanobody 1D22 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ... 著者 Shahine, A, Rossjohn, J. 登録日 2019-12-10 公開日 2020-09-16 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response. Nat Cancer, 2020
7JVC	SARS-CoV-2 spike in complex with the S2A4 neutralizing antibody Fab fragment 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2A4 Fab heavy chain, ... 著者 Park, Y.J, Tortorici, M.A, Walls, A.C, Czudnochowski, N, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G, Veesler, D. 登録日 2020-08-20 公開日 2020-10-14 最終更新日 2021-06-23 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology. Cell, 183, 2020
7JZI	Crystal structure of LAIR1 ectodomain (from MGD21) in complex with Plasmodium RIFIN (PF3D7_1040300) V2 domain 分子名称: LAIR1 ectodomain from antibody MGD21, PLATINUM (II) ION, Rifin 著者 Xu, K, Kwong, P.D. 登録日 2020-09-02 公開日 2021-05-26 最終更新日 2021-09-22 実験手法 X-RAY DIFFRACTION (2.707 Å) 主引用文献 Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs. Nat Commun, 12, 2021
7JZ4	Crystal structure of broadly Plasmodium RIFIN reactive LAIR1-inserted antibody MGD21 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MGD21 heavy chain, MGD21 light chain, ... 著者 Xu, K, Kwong, P.D. 登録日 2020-09-01 公開日 2021-05-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.747 Å) 主引用文献 Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs. Nat Commun, 12, 2021
7JZK	Crystal structure of LAIR1 ectodomain (from MGD21) in complex with Plasmodium RIFIN (PF3D7_0401300) V2 domain 分子名称: LAIR1 ecotodomain from MGD21 antibody, Rifin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Xu, K, Kwong, P.D. 登録日 2020-09-02 公開日 2021-05-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.457 Å) 主引用文献 Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs. Nat Commun, 12, 2021
7JZ1	Crystal structure of broadly Plasmodium RIFIN reactive LAIR1-inserted antibody MGC34 分子名称: MGC34 heavy chain, MGC34 light chain 著者 Xu, K, Kwong, P.D. 登録日 2020-09-01 公開日 2021-05-26 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.37 Å) 主引用文献 Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs. Nat Commun, 12, 2021
6W4W	Crystal Structure of the Fab fragment of humanized 5c8 antibody 分子名称: 5c8 Fab heavy chain, 5c8 Fab light chain 著者 Henderson, J.N, Mills, J.H, Simmons, C.R. 登録日 2020-03-11 公開日 2020-12-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Structural Insights into How Protein Environments Tune the Spectroscopic Properties of a Noncanonical Amino Acid Fluorophore. Biochemistry, 59, 2020
6NHA	Crystal structure of SYNT001, a human FcRn blocking monoclonal antibody 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Beta-2-microglobulin, IgG receptor FcRn large subunit p51, ... 著者 Blumberg, R.S, Cheung, J, Mahmood, A, Gandhi, A.K. 登録日 2018-12-21 公開日 2019-12-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.381 Å) 主引用文献 Blocking FcRn in humans reduces circulating IgG levels and inhibits IgG immune complex-mediated immune responses. Sci Adv, 5, 2019
6PE7	Crystal Structure of ABBV-323 FAB 分子名称: FAB Heavy Chain, FAB Light chain, SULFATE ION 著者 Argiriadi, M.A. 登録日 2019-06-20 公開日 2019-08-14 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches. BMC Mol Cell Biol, 20, 2019
6PI7	Crystal structure of the TDRD2 extended Tudor domain in complex with an antibody fragment and the PIWIL1 peptide 分子名称: Fab antigen-binding fragment, Piwi-like protein 1, Tudor and KH domain-containing protein, ... 著者 Liu, K, Min, J.R, Structural Genomics Consortium (SGC) 登録日 2019-06-26 公開日 2019-07-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Lesson from a Fab-enabled co-crystallization study of TDRD2 and PIWIL1. Methods, 175, 2020

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