7Y58

CryoEM structure of QacA (D411N), an antibacterial efflux transporter from Staphylococcus aureus

Summary for 7Y58

Entry DOI	10.2210/pdb7y58/pdb
EMDB information	33612
Descriptor	Antiseptic resistance protein, Single-domain Indian camelid antibody (A4), single-domain indian camelid antibody(B7) (3 entities in total)
Functional Keywords	drug proton antiporter, major facilitator superfamily(mfs), staphylococcus aureus, antibacterial efflux, qaca, membrane protein, membrane protein-immune system complex, membrane protein/immune system
Biological source	Staphylococcus aureus More
Total number of polymer chains	3
Total formula weight	82208.52
Authors	Penmatsa, A.,Majumder, P. (deposition date: 2022-06-16, release date: 2023-07-12, Last modification date: 2023-11-22)
Primary citation	Majumder, P.,Ahmed, S.,Ahuja, P.,Athreya, A.,Ranjan, R.,Penmatsa, A. Cryo-EM structure of antibacterial efflux transporter QacA from Staphylococcus aureus reveals a novel extracellular loop with allosteric role. Embo J., 42:e113418-e113418, 2023 Cited by PubMed: 37458117 DOI: 10.15252/embj.2023113418 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.8 Å)

Structure validation