6V7Y

Human CD1d presenting alpha-Galactosylceramide in complex with VHH nanobody 1D5

Summary for 6V7Y

• Entry DOI: 10.2210/pdb6v7y/pdb
• Descriptor: Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, Nanobody VHH ID5, ... (10 entities in total)
• Functional Keywords: lipid, nanobody, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 68106.72

Authors

Shahine, A.,Rossjohn, J. (deposition date: 2019-12-10, release date: 2020-09-16, Last modification date: 2023-10-11)

• Primary citation: Shahine, A.,Rossjohn, J.; A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response.; Nat Cancer, 2020; DOI: 10.1038/s43018-020-00111-6

Experimental method

X-RAY DIFFRACTION (2.4 Å)