7MMO

LY-CoV1404 neutralizing antibody against SARS-CoV-2

Summary for 7MMO

• Entry DOI: 10.2210/pdb7mmo/pdb
• Descriptor: LY-CoV1404 Fab heavy chain, LY-CoV1404 Fab light chain, Spike protein S1, ... (5 entities in total)
• Functional Keywords: antibody neutralizing sars-cov-2, immune system, immune system-viral protein complex, immune system/viral protein
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 140789.90

Authors

Hendle, J.,Pustilnik, A.,Sauder, J.M.,Coleman, K.A.,Boyles, J.S.,Dickinson, C.D. (deposition date: 2021-04-30, release date: 2021-05-12, Last modification date: 2023-10-18)

• Primary citation: Westendorf, K.,Wang, L.,Zentelis, S.,Foster, D.,Vaillancourt, P.,Wiggin, M.,Lovett, E.,van der Lee, R.,Hendle, J.,Pustilnik, A.,Sauder, J.M.,Kraft, L.,Hwang, Y.,Siegel, R.W.,Chen, J.,Heinz, B.A.,Higgs, R.E.,Kallewaard, N.,Jepson, K.,Goya, R.,Smith, M.A.,Collins, D.W.,Pellacani, D.,Xiang, P.,de Puyraimond, V.,Ricicova, M.,Devorkin, L.,Pritchard, C.,O'Neill, A.,Dalal, K.,Panwar, P.,Dhupar, H.,Garces, F.A.,Cohen, C.,Dye, J.,Huie, K.E.,Badger, C.V.,Kobasa, D.,Audet, J.,Freitas, J.J.,Hassanali, S.,Hughes, I.,Munoz, L.,Palma, H.C.,Ramamurthy, B.,Cross, R.W.,Geisbert, T.W.,Menacherry, V.,Lokugamage, K.,Borisevich, V.,Lanz, I.,Anderson, L.,Sipahimalani, P.,Corbett, K.S.,Yang, E.S.,Zhang, Y.,Shi, W.,Zhou, T.,Choe, M.,Misasi, J.,Kwong, P.D.,Sullivan, N.J.,Graham, B.S.,Fernandez, T.L.,Hansen, C.L.,Falconer, E.,Mascola, J.R.,Jones, B.E.,Barnhart, B.C.; LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants.; Biorxiv, 2022; PubMed: 33972947; DOI: 10.1101/2021.04.30.442182

Experimental method

X-RAY DIFFRACTION (2.427 Å)