4LDE
Structure of beta2 adrenoceptor bound to BI167107 and an engineered nanobody
Summary for 4LDE
Entry DOI | 10.2210/pdb4lde/pdb |
Related | 4LDL 4LDO |
Descriptor | Lysozyme, Beta-2 adrenergic receptor, Camelid Antibody Fragment, 8-[(1R)-2-{[1,1-dimethyl-2-(2-methylphenyl)ethyl]amino}-1-hydroxyethyl]-5-hydroxy-2H-1,4-benzoxazin-3(4H)-one, ... (6 entities in total) |
Functional Keywords | g protein coupled receptor, membrane protein-hydrolase complex, membrane protein/hydrolase |
Biological source | Enterobacteria phage T4 (human) More |
Cellular location | Cell membrane ; Multi- pass membrane protein : P07550 |
Total number of polymer chains | 2 |
Total formula weight | 67114.28 |
Authors | Ring, A.M.,Manglik, A.,Kruse, A.C.,Enos, M.D.,Weis, W.I.,Garcia, K.C.,Kobilka, B.K. (deposition date: 2013-06-24, release date: 2013-09-25, Last modification date: 2023-09-20) |
Primary citation | Ring, A.M.,Manglik, A.,Kruse, A.C.,Enos, M.D.,Weis, W.I.,Garcia, K.C.,Kobilka, B.K. Adrenaline-activated structure of beta 2-adrenoceptor stabilized by an engineered nanobody. Nature, 502:575-579, 2013 Cited by PubMed: 24056936DOI: 10.1038/nature12572 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.79 Å) |
Structure validation
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