4LDL

Structure of beta2 adrenoceptor bound to hydroxybenzylisoproterenol and an engineered nanobody

Summary for 4LDL

Related4LDE 4LDO
DescriptorLysozyme, Beta-2 adrenergic receptor, Camelid Antibody Fragment, 4-[(1R)-1-hydroxy-2-{[1-(4-hydroxyphenyl)-2-methylpropan-2-yl]amino}ethyl]benzene-1,2-diol, ... (6 entities in total)
Functional Keywordsg protein coupled receptor, membrane protein-hydrolase complex, membrane protein/hydrolase
Biological sourceEnterobacteria phage T4
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Cellular locationCell membrane ; Multi- pass membrane protein  P07550
Total number of polymer chains2
Total molecular weight67061.22
Authors
Ring, A.M.,Manglik, A.,Kruse, A.C.,Enos, M.D.,Weis, W.I.,Garcia, K.C.,Kobilka, B.K. (deposition date: 2013-06-24, release date: 2013-09-25, Last modification date: 2017-08-09)
Primary citation
Ring, A.M.,Manglik, A.,Kruse, A.C.,Enos, M.D.,Weis, W.I.,Garcia, K.C.,Kobilka, B.K.
Adrenaline-activated structure of beta 2-adrenoceptor stabilized by an engineered nanobody.
Nature, 502:575-579, 2013
PubMed: 24056936 (PDB entries with the same primary citation)
DOI: 10.1038/nature12572
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.1 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.255501.3%0.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4ldl
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Molmil generated image of 4ldl
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Molmil generated image of 4ldl
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