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6V7Z

Human CD1d presenting alpha-Galactosylceramide in complex with VHH nanobody 1D22

Summary for 6V7Z
Entry DOI10.2210/pdb6v7z/pdb
DescriptorAntigen-presenting glycoprotein CD1d, CHLORIDE ION, SULFATE ION, ... (14 entities in total)
Functional Keywordslipid, nanobody, immune system
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains6
Total formula weight132341.24
Authors
Shahine, A.,Rossjohn, J. (deposition date: 2019-12-10, release date: 2020-09-16, Last modification date: 2023-10-11)
Primary citationShahine, A.,Rossjohn, J.
A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response.
Nat Cancer, 2020
Cited by
DOI: 10.1038/s43018-020-00111-6
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.75 Å)
Structure validation

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