6V7Z

Human CD1d presenting alpha-Galactosylceramide in complex with VHH nanobody 1D22

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Antigen-presenting glycoprotein CD1d	polymer	347	39471.6	2	UniProt (P15813) Pfam (PF16497) Pfam (PF07654) In PDB	Homo sapiens (Human)	R3G1
2	B, D	Beta-2-microglobulin	polymer	100	11879.4	2	UniProt (P61769) Pfam (PF07654) In PDB	Homo sapiens (Human)
3	E, F	Nanobody VHH ID22	polymer	118	12614.9	2		Lama glama (llama)
4	G, J	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
5	H	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		383.3	1	In PDB GlyTouCan (G90333CG)
6	I	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
7	A	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
8	A, C	N-{(1S,2R,3S)-1-[(ALPHA-D-GALACTOPYRANOSYLOXY)METHYL]-2,3-DIHYDROXYHEPTADECYL}HEXACOSANAMIDE	non-polymer		858.3	2	Chemie (AGH)
9	A, E	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	3	Chemie (PEG)
10	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
11	B	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
12	B	beta-D-glucopyranose	non-polymer		180.2	1	Chemie (BGC)
13	D	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
14		water	water		18.0	64	Chemie (HOH)

Sequence modifications

A, C: 5 - 278 (UniProt: P15813)

PDB	External Database	Details
Met 4	-	initiating methionine

A, C: 279 - 350 (PDB: 6V7Z)
B, D: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	127931.7
Branched	Number of molecules	4
	Total formula weight	1818.7
Non-Polymers*	Number of molecules	10
	Total formula weight	2590.9
All*	Total formula weight	132341.2

*Water molecules are not included.