7JZ4

Crystal structure of broadly Plasmodium RIFIN reactive LAIR1-inserted antibody MGD21

Summary for 7JZ4

• Entry DOI: 10.2210/pdb7jz4/pdb
• Descriptor: MGD21 heavy chain, MGD21 light chain, PHOSPHATE ION, ... (5 entities in total)
• Functional Keywords: lair1, insertion, antibody, rifin, malaria, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 4
• Total formula weight: 126126.51

Authors

Xu, K.,Kwong, P.D. (deposition date: 2020-09-01, release date: 2021-05-26, Last modification date: 2023-10-18)

• Primary citation: Xu, K.,Wang, Y.,Shen, C.H.,Chen, Y.,Zhang, B.,Liu, K.,Tsybovsky, Y.,Wang, S.,Farney, S.K.,Gorman, J.,Stephens, T.,Verardi, R.,Yang, Y.,Zhou, T.,Chuang, G.Y.,Lanzavecchia, A.,Piccoli, L.,Kwong, P.D.; Structural basis of LAIR1 targeting by polymorphic Plasmodium RIFINs.; Nat Commun, 12:4226-4226, 2021; PubMed: 34244481; DOI: 10.1038/s41467-021-24291-6

Experimental method

X-RAY DIFFRACTION (2.747 Å)