PDB: 1466 件ウェブページステータス検索Chemie searchBIRD

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7ABI	Human pre-Bact-2 spliceosome 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Beta-catenin-like protein 1, ... 著者 Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. 登録日 2020-09-07 公開日 2021-02-10 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
7ABF	Human pre-Bact-1 spliceosome core structure 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. 登録日 2020-09-07 公開日 2020-12-09 最終更新日 2020-12-30 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
7AAV	Human pre-Bact-2 spliceosome core structure 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, D-chiro inositol hexakisphosphate, ... 著者 Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. 登録日 2020-09-04 公開日 2020-12-09 最終更新日 2020-12-30 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
7JXV	ANTH domain of CALM (clathrin-assembly lymphoid myeloid leukemia protein) bound to ubiquitin 分子名称: Phosphatidylinositol-binding clathrin assembly protein, Ubiquitin 著者 Pashkova, N, Gakhar, L, Schnicker, N.J, Piper, R.C. 登録日 2020-08-28 公開日 2021-08-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 ANTH domains within CALM, HIP1R, and Sla2 recognize ubiquitin internalization signals. Elife, 10, 2021
7JTP	Crystal structure of Protac MS67 in complex with the WD repeat-containing protein 5 and pVHL:ElonginC:ElonginB 分子名称: Elongin-B, Elongin-C, GLYCEROL, ... 著者 Kottur, J, Jain, R, Aggarwal, A.K. 登録日 2020-08-18 公開日 2021-10-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models. Sci Transl Med, 13, 2021
7JTO	Crystal structure of Protac MS33 in complex with the WD repeat-containing protein 5 and pVHL:ElonginC:ElonginB 分子名称: 1,2-ETHANEDIOL, 3-methyl-N-(11-{[2-(4-{[4'-(4-methylpiperazin-1-yl)-3'-{[6-oxo-4-(trifluoromethyl)-5,6-dihydropyridine-3-carbonyl]amino}[1,1'-biphenyl]-3-yl]methyl}piperazin-1-yl)ethyl]amino}-11-oxoundecanoyl)-L-valyl-(4R)-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}-L-prolinamide, Elongin-B, ... 著者 Kottur, J, Jain, R, Aggarwal, A.K. 登録日 2020-08-18 公開日 2021-10-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models. Sci Transl Med, 13, 2021
7JQC	SARS-CoV-2 Nsp1, CrPV IRES and rabbit 40S ribosome complex 分子名称: 40S ribosomal protein S21, 40S ribosomal protein S24, 40S ribosomal protein S26, ... 著者 Yuan, S, Xiong, Y. 登録日 2020-08-10 公開日 2020-12-02 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA. Mol.Cell, 80, 2020
7JQB	SARS-CoV-2 Nsp1 and rabbit 40S ribosome complex 分子名称: 40S ribosomal protein S21, 40S ribosomal protein S24, 40S ribosomal protein S26, ... 著者 Yuan, S, Xiong, Y. 登録日 2020-08-10 公開日 2020-12-02 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA. Mol.Cell, 80, 2020
7CPV	Cryo-EM structure of 80S ribosome from mouse testis 分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ... 著者 Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H. 登録日 2020-08-08 公開日 2022-02-02 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.03 Å) 主引用文献 A male germ-cell-specific ribosome controls male fertility. Nature, 612, 2022
7CPU	Cryo-EM structure of 80S ribosome from mouse kidney 分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S13, ... 著者 Huo, Y.G, He, X, Jiang, T, Qin, Y, Guo, X.J, Sha, J.H. 登録日 2020-08-08 公開日 2022-02-02 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.82 Å) 主引用文献 A male germ-cell-specific ribosome controls male fertility. Nature, 612, 2022
7A09	Structure of a human ABCE1-bound 43S pre-initiation complex - State III 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-08-07 公開日 2020-10-14 最終更新日 2021-01-13 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. Embo J., 40, 2021
7A01	The Halastavi arva virus intergenic region IRES promotes translation by the simplest possible initiation mechanism 分子名称: 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES21, ... 著者 Abaeva, I, Vicens, Q, Bochler, A, Soufari, H, Simonetti, A, Pestova, T.V, Hashem, Y, Hellen, C.U.T. 登録日 2020-08-05 公開日 2020-12-30 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism. Cell Rep, 33, 2020
7JMS	Structure of the Hazara virus OTU bound to ubiquitin 分子名称: CALCIUM ION, GLYCEROL, Polyubiquitin-B, ... 著者 Dzimianski, J.V, Pegan, S.D. 登録日 2020-08-02 公開日 2020-10-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Flipping the substrate preference of Hazara virus ovarian tumour domain protease through structure-based mutagenesis. Acta Crystallogr D Struct Biol, 76, 2020
6ZXE	Cryo-EM structure of a late human pre-40S ribosomal subunit - State F2 分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R. 登録日 2020-07-29 公開日 2020-12-02 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis for the final steps of human 40S ribosome maturation. Nature, 587, 2020
6ZXD	Cryo-EM structure of a late human pre-40S ribosomal subunit - State F1 分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R. 登録日 2020-07-29 公開日 2020-12-02 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural basis for the final steps of human 40S ribosome maturation. Nature, 587, 2020
6ZXF	Cryo-EM structure of a late human pre-40S ribosomal subunit - State G 分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R. 登録日 2020-07-29 公開日 2020-12-02 最終更新日 2020-12-09 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis for the final steps of human 40S ribosome maturation. Nature, 587, 2020
6ZXG	Cryo-EM structure of a late human pre-40S ribosomal subunit - State H1 分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R. 登録日 2020-07-29 公開日 2020-12-02 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structural basis for the final steps of human 40S ribosome maturation. Nature, 587, 2020
6ZXH	Cryo-EM structure of a late human pre-40S ribosomal subunit - State H2 分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R. 登録日 2020-07-29 公開日 2020-12-16 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structural basis for the final steps of human 40S ribosome maturation. Nature, 587, 2020
6ZV6	Human RIO1(kd)-StHA late pre-40S particle, structural state B (post 18S rRNA cleavage) 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Plassart, L, Shayan, R, Plisson-Chastang, C. 登録日 2020-07-24 公開日 2021-05-12 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 The final step of 40S ribosomal subunit maturation is controlled by a dual key lock. Elife, 10, 2021
6ZUO	Human RIO1(kd)-StHA late pre-40S particle, structural state A (pre 18S rRNA cleavage) 分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Plassart, L, Shayan, R, Plisson-Chastang, C. 登録日 2020-07-23 公開日 2021-05-12 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 The final step of 40S ribosomal subunit maturation is controlled by a dual key lock. Elife, 10, 2021
6ZU9	Structure of a yeast ABCE1-bound 48S initiation complex 分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... 著者 Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-07-22 公開日 2020-10-28 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes. Embo J., 40, 2021
7CJB	VHL recognizes hydroxyproline in RIPK1 分子名称: Elongin-B, Elongin-C, GLYCEROL, ... 著者 Liu, J, Wang, Y, Pan, L. 登録日 2020-07-09 公開日 2021-07-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 VHL recognizes hydroxyproline in RIPK1 To Be Published
6XQC	UbKEKS 分子名称: Polyubiquitin-B 著者 Delattre, P, Letourneau, D, Lavigne, P, Roucou, X, Boisvert, F.M. 登録日 2020-07-09 公開日 2021-05-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution NMR structure of UbKEKS To Be Published
6ZQH	Yeast Uba1 in complex with ubiquitin 分子名称: BETA-MERCAPTOETHANOL, GLYCEROL, TETRAETHYLENE GLYCOL, ... 著者 Misra, M, Schindelin, H. 登録日 2020-07-09 公開日 2020-11-04 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.032 Å) 主引用文献 Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection. Chemistry, 27, 2021
6ZP4	SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 2 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2020-07-08 公開日 2020-07-29 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. Science, 369, 2020

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