7M4M
Crystal structure of RBR E3 ligase RNF216 with ubiquitin
Summary for 7M4M
| Entry DOI | 10.2210/pdb7m4m/pdb |
| Descriptor | E3 ubiquitin-protein ligase RNF216, Ubiquitin, ZINC ION, ... (5 entities in total) |
| Functional Keywords | e3 ligase, rbr, ubiquitin, enzyme, ligase |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 81252.32 |
| Authors | Cotton, T.R.,Lechtenberg, B.C. (deposition date: 2021-03-21, release date: 2022-01-05, Last modification date: 2024-04-03) |
| Primary citation | Cotton, T.R.,Cobbold, S.A.,Bernardini, J.P.,Richardson, L.W.,Wang, X.S.,Lechtenberg, B.C. Structural basis of K63-ubiquitin chain formation by the Gordon-Holmes syndrome RBR E3 ubiquitin ligase RNF216. Mol.Cell, 82:598-615.e8, 2022 Cited by PubMed: 34998453DOI: 10.1016/j.molcel.2021.12.005 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.39 Å) |
Structure validation
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