PDB: 491 件ウェブページステータス検索Chemie searchBIRD

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4U54	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N-methyl-1-[3-(pyridin-3-yl)phenyl]methanamine 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-24 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5S	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N-[(2S)-2-[(N~2~-acetyl-D-lysyl)amino]-3-(pyridin-3-ylmethoxy)propyl]-L-allothreonyl-D-phenylalaninamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-25 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U5U	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N~2~-[3-(pyridin-3-yl)benzyl]-L-lysinamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-25 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
4U58	IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR 分子名称: Importin subunit alpha-1, N~2~-[4-(pyridin-3-yl)benzoyl]-L-lysinamide 著者 Stewart, M, Valkov, E, Holvey, R.S. 登録日 2014-07-24 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Selective Targeting of the TPX2 Site of Importin-alpha Using Fragment-Based Ligand Design. Chemmedchem, 10, 2015
7RG1	Importin alpha2 in complex with MERS ORF4B H26A mutant 分子名称: Importin subunit alpha-1, ORF4b 著者 Munasinghe, T.S, Tsimbalyuk, S, Roby, J.A, Aragao, D, Forwood, J.K. 登録日 2021-07-14 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Importin alpha2 in complex with MERS ORF4B NLS H26A mutant To Be Published
5XBK	Crystal structure of human Importin4 分子名称: Importin-4, histone H3 著者 Song, J.J, Yoon, J. 登録日 2017-03-20 公開日 2018-02-14 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.223 Å) 主引用文献 Integrative Structural Investigation on the Architecture of Human Importin4_Histone H3/H4_Asf1a Complex and Its Histone H3 Tail Binding J. Mol. Biol., 430, 2018
2XWU	CRYSTAL STRUCTURE OF IMPORTIN 13 - UBC9 COMPLEX 分子名称: IMPORTIN13, SUMO-CONJUGATING ENZYME UBC9 著者 Gruenwald, M, Bono, F. 登録日 2010-11-05 公開日 2010-12-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of Importin13-Ubc9 Complex: Nuclear Import and Release of a Key Regulator of Sumoylation. Embo J., 30, 2011
3LWW	Structure of an open and closed conformation of Human Importin Beta bound to the Snurportin1 IBB-domain trapped in the same crystallographic asymmetric unit 分子名称: Importin subunit beta-1, Snurportin-1 著者 Bhardwaj, A, Cingolani, G. 登録日 2010-02-24 公開日 2010-06-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Conformational selection in the recognition of the snurportin importin beta binding domain by importin beta. Biochemistry, 49, 2010
3L3Q	Mouse importin alpha-pepTM NLS peptide complex 分子名称: CITRATE ANION, Importin subunit alpha-2, pepTM 著者 Takeda, A.A.S, Kobe, B, Fontes, M.R.M. 登録日 2009-12-17 公開日 2010-04-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Probing the specificity of binding to the major nuclear localization sequence-binding site of importin-alpha using oriented peptide library screening. J.Biol.Chem., 285, 2010
3KND	TPX2:importin-alpha complex 分子名称: Importin subunit alpha-2, SULFATE ION, Targeting protein for Xklp2 著者 Stewart, M. 登録日 2009-11-12 公開日 2010-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.151 Å) 主引用文献 Novel binding of the mitotic regulator TPX2 (target protein for Xenopus kinesin-like protein 2) to importin-alpha. J.Biol.Chem., 285, 2010
7N9H	Structure of the mammalian importin a1 bound to the TDP-43 NLS 分子名称: Importin subunit alpha-1, TAR DNA-binding protein 43 著者 Doll, S.G, Lokareddy, R.K, Cingolani, G. 登録日 2021-06-17 公開日 2022-06-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Recognition of the TDP-43 nuclear localization signal by importin alpha 1/ beta. Cell Rep, 39, 2022
5W41	Zika MR766 NLS in complex with Importin alpha subunit-1 分子名称: Importin subunit alpha-1, ZIKA MR766 NLS 著者 Jeffress, S, Smith, K.M, Forwood, J.K. 登録日 2017-06-08 公開日 2018-06-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Zika virus NS5 forms supramolecular nuclear bodies that sequester importin alpha and modulate the host immune and pro-inflammatory response in neuronal cells. ACS Infect Dis, 2019
7UNK	Structure of Importin-4 bound to the H3-H4-ASF1 histone-histone chaperone complex 分子名称: Histone H3, Histone H4, Histone chaperone, ... 著者 Bernardes, N.E, Chook, Y.M, Fung, H.Y.J, Chen, Z, Li, Y. 登録日 2022-04-11 公開日 2022-09-21 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Structure of IMPORTIN-4 bound to the H3-H4-ASF1 histone-histone chaperone complex. Proc.Natl.Acad.Sci.USA, 119, 2022
2C1M	Nup50:importin-alpha complex 分子名称: IMPORTIN-ALPHA2 SUBUNIT, NUCLEOPORIN 50 KDA 著者 Matsuura, Y, Stewart, M. 登録日 2005-09-16 公開日 2005-11-23 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Nup50/Npap60 Function in Nuclear Protein Import Complex Disassembly and Importin Recycling. Embo J., 24, 2005
3ND2	Structure of Yeast Importin-beta (Kap95p) 分子名称: Importin subunit beta-1 著者 Forwood, J.K, Kobe, B. 登録日 2010-06-06 公開日 2010-07-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Quantitative Structural Analysis of Importin-beta Flexibility: Paradigm for Solenoid Protein Structures Structure, 18, 2010
1Y2A	Structure of mammalian importin bound to the non-classical PLSCR1-NLS 分子名称: Importin alpha-2 Subunit, decamer fragment of Phospholipid scramblase 1 著者 Chen, M.-H, Ben-Efraim, I, Mitrousis, G, Walker-Kopp, N, Sims, P.J, Cingolani, G. 登録日 2004-11-22 公開日 2005-02-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Phospholipid Scramblase 1 Contains a Nonclassical Nuclear Localization Signal with Unique Binding Site in Importin alpha J.Biol.Chem., 280, 2005
3OQS	Crystal structure of importin-alpha bound to a CLIC4 NLS peptide 分子名称: Importin subunit alpha-2, peptide of Chloride intracellular channel protein 4 著者 Mynott, A.V, Brown, L.J, Harrop, S.J, Curmi, P.M.G. 登録日 2010-09-03 公開日 2011-07-27 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of importin-alpha bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4 Febs J., 278, 2011
7TMX	Structure of Mouse Importin alpha NEIL1 NLS Peptide Complex 分子名称: Importin subunit alpha-1, Nuclear Localization Signal from Endonuclease 8-like 1 著者 Moraes, I.R, de Oliveira, H.C, Fontes, M.R.M. 登録日 2022-01-20 公開日 2023-08-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of nuclear transport for NEIL DNA glycosylases mediated by importin-alpha. Biochim Biophys Acta Proteins Proteom, 1872, 2023
7TMY	Structure of Mouse Importin alpha NEIL3 NLS Peptide Complex 分子名称: Importin subunit alpha-1, Nuclear Localization Signal from Endonuclease 8-like 3 著者 Moraes, I.R, de Oliveira, H.C, Fontes, M.R.M. 登録日 2022-01-20 公開日 2023-08-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structural basis of nuclear transport for NEIL DNA glycosylases mediated by importin-alpha. Biochim Biophys Acta Proteins Proteom, 1872, 2023
1UKL	Crystal structure of Importin-beta and SREBP-2 complex 分子名称: Importin beta-1 subunit, Sterol regulatory element binding protein-2 著者 Lee, S.J, Sekimoto, T, Yamashita, E, Nagoshi, E, Nakagawa, A, Imamoto, N, Yoshimura, M, Sakai, H, Tsukihara, T, Yoneda, Y. 登録日 2003-08-26 公開日 2003-12-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The Structure of Importin-beta Bound to SREBP-2: Nuclear Import of a Transcription Factor Science, 302, 2003
1IQ1	CRYSTAL STRUCTURE OF THE IMPORTIN-ALPHA(44-54)-IMPORTIN-ALPHA(70-529) COMPLEX 分子名称: IMPORTIN ALPHA-2 SUBUNIT 著者 Catimel, B, Teh, T, Fontes, M.R.M, Jennings, I.G, Kobe, B. 登録日 2001-05-28 公開日 2001-11-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Biophysical characterization of interactions involving importin-alpha during nuclear import. J.Biol.Chem., 276, 2001
1M5N	Crystal structure of HEAT repeats (1-11) of importin b bound to the non-classical NLS(67-94) of PTHrP 分子名称: Importin beta-1 subunit, Parathyroid hormone-related protein 著者 Cingolani, G, Bednenko, J, Gillespie, M.T, Gerace, L. 登録日 2002-07-09 公開日 2003-01-21 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Molecular basis for the recognition of a nonclassical nuclear localization signal by importin beta Mol.Cell, 10, 2002
6IW8	Crystal structure of Importin-alpha and wild-type GM130 分子名称: Importin subunit alpha-1, Peptide from Golgin subfamily A member 2 著者 Chang, C.-C, Chen, C.-J, Pien, Y.-C, Tsai, S.-Y, Hsia, K.-C. 登録日 2018-12-04 公開日 2019-10-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-alpha. Nat Commun, 10, 2019
6IWA	Crystal structure of Importin-alpha and phosphoserine GM130 分子名称: Importin subunit alpha-1, PHOSPHOSERINE GM130 著者 Chang, C.-C, Chen, C.-J, Pien, Y.-C, Tsai, S.-Y, Hsia, K.-C. 登録日 2018-12-05 公開日 2019-10-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-alpha. Nat Commun, 10, 2019
6K06	Crystal structure of Importin-alpha and phosphomimetic GM130 分子名称: Importin subunit alpha-1, Peptide from Golgin subfamily A member 2 著者 Chang, C.-C, Chen, C.-J, Pien, Y.-C, Tsai, S.-Y, Hsia, K.-C. 登録日 2019-05-05 公開日 2019-10-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-alpha. Nat Commun, 10, 2019

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