1Y2A

Structure of mammalian importin bound to the non-classical PLSCR1-NLS

Summary for 1Y2A

Entry DOI	10.2210/pdb1y2a/pdb
Related	1EE5 1EJL 1IAL 1PJM 1QGK
Descriptor	Importin alpha-2 Subunit, decamer fragment of Phospholipid scramblase 1 (3 entities in total)
Functional Keywords	armadillo repeat; protein:peptide complex; superhelix of helices, protein transport
Biological source	Mus musculus (house mouse) More
Cellular location	Cytoplasm (By similarity): P52293 Membrane; Single-pass type II membrane protein: O15162
Total number of polymer chains	2
Total formula weight	47515.39
Authors	Chen, M.-H.,Ben-Efraim, I.,Mitrousis, G.,Walker-Kopp, N.,Sims, P.J.,Cingolani, G. (deposition date: 2004-11-22, release date: 2005-02-01, Last modification date: 2024-02-14)
Primary citation	Chen, M.-H.,Ben-Efraim, I.,Mitrousis, G.,Walker-Kopp, N.,Sims, P.J.,Cingolani, G. Phospholipid Scramblase 1 Contains a Nonclassical Nuclear Localization Signal with Unique Binding Site in Importin alpha J.Biol.Chem., 280:10599-10606, 2005 Cited by PubMed: 15611084 DOI: 10.1074/jbc.M413194200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation