1M5N

Crystal structure of HEAT repeats (1-11) of importin b bound to the non-classical NLS(67-94) of PTHrP

Summary for 1M5N

Related1QGK 1QGR
DescriptorImportin beta-1 subunit, Parathyroid hormone-related protein (3 entities in total)
Functional Keywordsall helical protein, heat repeats, protein transport
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm Q14974 P12272
Total number of polymer chains2
Total molecular weight57170.1
Authors
Cingolani, G.,Bednenko, J.,Gillespie, M.T.,Gerace, L. (deposition date: 2002-07-09, release date: 2003-01-21, Last modification date: 2011-07-13)
Primary citation
Cingolani, G.,Bednenko, J.,Gillespie, M.T.,Gerace, L.
Molecular basis for the recognition of a nonclassical nuclear localization signal by importin beta
Mol.Cell, 10:1345-1353, 2002
PubMed: 12504010 (PDB entries with the same primary citation)
DOI: 10.1016/S1097-2765(02)00727-X
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.9 Å)
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers57 12.2% 8.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02