3OQS

Crystal structure of importin-alpha bound to a CLIC4 NLS peptide

Summary for 3OQS

Descriptorpeptide of Chloride intracellular channel protein 4, Importin subunit alpha-2 (3 entities in total)
Functional Keywordsimportin alpha, karyopherin alpha, nuclear localisation signal (nls) recognition, chloride intracellular channel 4, clic4 nls, armadillo repeat, nuclear import, protein transport
Biological sourceMus musculus (mouse)
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Cellular locationCytoplasm, cytoskeleton, centrosome Q9Y696
Cytoplasm (By similarity) P52293
Total number of polymer chains2
Total molecular weight56539.06
Authors
Mynott, A.V.,Brown, L.J.,Harrop, S.J.,Curmi, P.M.G. (deposition date: 2010-09-03, release date: 2011-07-27)
Primary citation
Mynott, A.V.,Harrop, S.J.,Brown, L.J.,Breit, S.N.,Kobe, B.,Curmi, P.M.G.
Crystal structure of importin-alpha bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4
Febs J., 278:1662-1675, 2011
PubMed: 21388519 (PDB entries with the same primary citation)
DOI: 10.1111/j.1742-4658.2011.08086.x
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.21790.2%1.4%7.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3oqs
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Molmil generated image of 3oqs
rotated about x axis by 90°
Molmil generated image of 3oqs
rotated about y axis by 90°