3OQS
Crystal structure of importin-alpha bound to a CLIC4 NLS peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | peptide of Chloride intracellular channel protein 4 | polymer | 10 | 1208.5 | 1 | UniProt (Q9Y696) | Homo sapiens | Intracellular chloride ion channel protein p64H1 |
| 2 | B (A) | Importin subunit alpha-2 | polymer | 510 | 55330.6 | 1 | UniProt (P52293) Pfam (PF01749) Pfam (PF00514) Pfam (PF16186) | Mus musculus (mouse) | Karyopherin subunit alpha-2, SRP1-alpha, RAG cohort protein 1, Pendulin, Pore targeting complex 58 kDa subunit, PTAC58, Importin alpha P1 |
| 3 | C, D (B, A) | water | water | 18.0 | 356 | Chemie (HOH) |
Sequence modifications
A: 70 - 529 (UniProt: P52293)
| PDB | External Database | Details |
|---|---|---|
| Met 20 | - | expression tag |
| His 21 | - | expression tag |
| His 22 | - | expression tag |
| His 23 | - | expression tag |
| His 24 | - | expression tag |
| His 25 | - | expression tag |
| His 26 | - | expression tag |
| Ser 27 | - | expression tag |
| Ser 28 | - | expression tag |
| Gly 29 | - | expression tag |
| Leu 30 | - | expression tag |
| Val 31 | - | expression tag |
| Pro 32 | - | expression tag |
| Arg 33 | - | expression tag |
| Gly 34 | - | expression tag |
| Ser 35 | - | expression tag |
| Gly 36 | - | expression tag |
| Met 37 | - | expression tag |
| Lys 38 | - | expression tag |
| Glu 39 | - | expression tag |
| Thr 40 | - | expression tag |
| Ala 41 | - | expression tag |
| Ala 42 | - | expression tag |
| Ala 43 | - | expression tag |
| Lys 44 | - | expression tag |
| Phe 45 | - | expression tag |
| Glu 46 | - | expression tag |
| Arg 47 | - | expression tag |
| Gln 48 | - | expression tag |
| His 49 | - | expression tag |
| Met 50 | - | expression tag |
| Asp 51 | - | expression tag |
| Ser 52 | - | expression tag |
| Pro 53 | - | expression tag |
| Asp 54 | - | expression tag |
| Leu 55 | - | expression tag |
| Gly 56 | - | expression tag |
| Thr 57 | - | expression tag |
| Asp 58 | - | expression tag |
| Asp 59 | - | expression tag |
| Asp 60 | - | expression tag |
| Asp 61 | - | expression tag |
| Lys 62 | - | expression tag |
| Ala 63 | - | expression tag |
| Met 64 | - | expression tag |
| Ala 65 | - | expression tag |
| Asp 66 | - | expression tag |
| Ile 67 | - | expression tag |
| Gly 68 | - | expression tag |
| Ser 69 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56539.1 | |
| All* | Total formula weight | 56539.1 |
