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2LOH
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Dimeric structure of transmembrane domain of amyloid precursor protein in micellar environment
分子名称: P3(42)
著者Nadezhdin, K, Bocharov, E, Bocharova, O, Arseniev, A.
登録日2012-01-24
公開日2012-05-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Dimeric structure of transmembrane domain of amyloid precursor protein in micellar environment.
Febs Lett., 586, 2012
2LP1
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The solution NMR structure of the transmembrane C-terminal domain of the amyloid precursor protein (C99)
分子名称: C99
著者Barrett, P.J, Song, Y, Van Horn, W.D, Hustedt, E.J, Schafer, J.M, Hadziselimovic, A, Beel, A.J, Sanders, C.R.
登録日2012-01-30
公開日2012-06-06
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The amyloid precursor protein has a flexible transmembrane domain and binds cholesterol.
Science, 336, 2012
2LZ3
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Solution NMR structure of transmembrane domain of amyloid precursor protein WT
分子名称: Amyloid beta A4 protein
著者Chen, W, Wang, C.
登録日2012-09-23
公開日2013-10-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Familial Alzheimer's mutations within APPTM increase A beta 42 production by enhancing accessibility of epsilon-cleavage site.
Nat Commun, 5, 2014
2LZ4
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Solution NMR structure of transmembrane domain of amyloid precursor protein V44M
分子名称: Amyloid beta A4 protein
著者Chen, W, Wang, C.
登録日2012-09-23
公開日2013-10-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Familial Alzheimer's mutations within APPTM increase A beta 42 production by enhancing accessibility of epsilon-cleavage site.
Nat Commun, 5, 2014
4HIX
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BU of 4hix by Molmil
Crystal structure of a humanised 3D6 Fab bound to amyloid beta peptide
分子名称: Beta-amyloid protein 40, Humanized 3D6 Fab heavy chain, Humanized 3D6 Fab light chain
著者Miles, L.A, Crespi, G.A.N, Parker, M.W.
登録日2012-10-12
公開日2013-03-13
最終更新日2014-03-19
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation.
Sci Rep, 3, 2013
2M4J
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BU of 2m4j by Molmil
40-residue beta-amyloid fibril derived from Alzheimer's disease brain
分子名称: Amyloid beta A4 protein
著者Lu, J, Qiang, W, Meredith, S.C, Yau, W, Schweiters, C.D, Tycko, R.
登録日2013-02-05
公開日2013-09-25
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Molecular Structure of beta-Amyloid Fibrils in Alzheimer's Disease Brain Tissue.
Cell(Cambridge,Mass.), 154, 2013
2M9R
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3D NMR structure of a complex between the amyloid beta peptide (1-40) and the polyphenol epsilon-viniferin glucoside
分子名称: (2S,3S)-3-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-6-yl beta-D-glucopyranoside, Amyloid beta A4 protein
著者Monti, J, Richard, T.
登録日2013-06-19
公開日2013-09-11
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献3D NMR structure of a complex between the amyloid beta peptide (1-40) and the polyphenol epsilon-viniferin glucoside: Implications in Alzheimer's disease.
Biochim.Biophys.Acta, 1830, 2013
2M9S
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3D NMR structure of a complex between the amyloid beta peptide (1-40) and the polyphenol epsilon-viniferin glucoside
分子名称: (2S,3S)-3-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydro-1-benzofuran-6-yl beta-D-glucopyranoside, Amyloid beta A4 protein
著者Monti, J, Richard, T.
登録日2013-06-19
公開日2013-09-11
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献3D NMR structure of a complex between the amyloid beta peptide (1-40) and the polyphenol epsilon-viniferin glucoside: Implications in Alzheimer's disease.
Biochim.Biophys.Acta, 1830, 2013
4M1C
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BU of 4m1c by Molmil
Crystal Structure Analysis of Fab-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Amyloid-Beta (1-40)
分子名称: Amyloid beta A4 protein, Fab-bound IDE, heavy chain, ...
著者McCord, L.M, Liang, W, Farcasanu, M, Scherpelz, K, Meredith, S.C, Koide, S, Tang, W.J.
登録日2013-08-02
公開日2014-08-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.5007 Å)
主引用文献Crystal Structure Analysis of Fab-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Amyloid-Beta (1-40)
To be Published
4MVL
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BU of 4mvl by Molmil
Crystal structure of an engineered lipocalin (Anticalin H1GA) in complex with the Alzheimer amyloid peptide Abeta1-40
分子名称: Beta-amyloid protein 40, Neutrophil gelatinase-associated lipocalin
著者Eichinger, A, Skerra, A.
登録日2013-09-24
公開日2015-08-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer beta-amyloid peptide.
Biochem.J., 473, 2016
4MVI
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BU of 4mvi by Molmil
Crystal structure of an engineered lipocalin (Anticalin US7) in complex with the Alzheimer amyloid peptide Abeta(1-40)
分子名称: Beta-amyloid protein 40, Neutrophil gelatinase-associated lipocalin
著者Eichinger, A, Skerra, A.
登録日2013-09-24
公開日2015-08-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer beta-amyloid peptide.
Biochem.J., 473, 2016
4NGE
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BU of 4nge by Molmil
Crystal Structure of Human Presequence Protease in Complex with Amyloid-beta (1-40)
分子名称: ACETATE ION, Beta-amyloid protein 40, GLYCEROL, ...
著者King, J.V, Liang, W.G, Tang, W.J.
登録日2013-11-01
公開日2014-05-14
最終更新日2014-07-23
実験手法X-RAY DIFFRACTION (2.704 Å)
主引用文献Molecular basis of substrate recognition and degradation by human presequence protease.
Structure, 22, 2014
2MJ1
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BU of 2mj1 by Molmil
NMR structure of the soluble A beta 17-34 peptide
分子名称: Amyloid beta A4 protein
著者Fonar, G, Samson, A.O.
登録日2013-12-23
公開日2014-11-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure of the water soluble A beta 17-34 peptide.
Biosci.Rep., 34, 2014
4ONG
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BU of 4ong by Molmil
Fab fragment of 3D6 in complex with amyloid beta 1-40
分子名称: 3D6 FAB ANTIBODY HEAVY CHAIN, 3D6 FAB ANTIBODY LIGHT CHAIN, Amyloid beta A4 protein, ...
著者Feinberg, H, Saldanha, J.W, Diep, L, Goel, A, Widom, A, Veldman, G.M, Weis, W.I, Schenk, D, Basi, G.S.
登録日2014-01-28
公開日2014-06-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure reveals conservation of amyloid-beta conformation recognized by 3D6 following humanization to bapineuzumab.
Alzheimers Res Ther, 6, 2014
2MPZ
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BU of 2mpz by Molmil
Atomic model of the Abeta D23N "Iowa" mutant using solid-state NMR, EM and Rosetta modeling
分子名称: Amyloid beta A4 protein
著者Sgourakis, N.G, Qiang, W.
登録日2014-06-10
公開日2015-04-22
最終更新日2024-05-01
実験手法SOLID-STATE NMR
主引用文献Modeling an in-register, parallel "iowa" a beta fibril structure using solid-state NMR data from labeled samples with rosetta.
Structure, 23, 2015
2MVX
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BU of 2mvx by Molmil
Atomic-resolution 3D structure of amyloid-beta fibrils: the Osaka mutation
分子名称: Amyloid beta A4 protein
著者Schuetz, A.K, Vagt, T, Huber, M, Ovchinnikova, O.Y, Cadalbert, R, Wall, J, Guentert, P, Bockmann, A, Glockshuber, R, Meier, B.H.
登録日2014-10-17
公開日2014-11-26
最終更新日2024-05-01
実験手法SOLID-STATE NMR
主引用文献Atomic-Resolution Three-Dimensional Structure of Amyloid beta Fibrils Bearing the Osaka Mutation.
Angew.Chem.Int.Ed.Engl., 54, 2015
2MXU
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BU of 2mxu by Molmil
42-Residue Beta Amyloid Fibril
分子名称: Amyloid beta A4 protein
著者Xiao, Y, Ma, B, McElheny, D, Parthasarathy, S, Long, F, Hoshi, M, Nussinov, R, Ishii, Y.
登録日2015-01-14
公開日2015-05-06
最終更新日2024-05-01
実験手法SOLID-STATE NMR
主引用文献A beta (1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease.
Nat.Struct.Mol.Biol., 22, 2015
4XXD
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BU of 4xxd by Molmil
Crystal Structure of mid-region amyloid beta capture by solanezumab
分子名称: Amyloid-beta fragment, Fab Heavy Chain, Fab Light Chain
著者Hermans, S.J, Crespi, G.A.N, Parker, M.W, Miles, L.A.
登録日2015-01-30
公開日2015-04-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Molecular basis for mid-region amyloid-beta capture by leading Alzheimer's disease immunotherapies.
Sci Rep, 5, 2015
5BUO
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BU of 5buo by Molmil
A receptor molecule
分子名称: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ACETATE ION, Amyloid beta A4 protein, ...
著者Gao, C, Crespi, G.A.N, Gorman, M.A, Nero, T.L, Parker, M.W, Miles, L.A.
登録日2015-06-04
公開日2016-07-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献NULL
To Be Published
5AEF
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BU of 5aef by Molmil
Electron cryo-microscopy of an Abeta(1-42)amyloid fibril
分子名称: AMYLOID BETA A4 PROTEIN
著者Schmidt, M, Rohou, A, Lasker, K, Yadav, J.K, Schiene-Fischer, C, Fandrich, M, Grigorieff, N.
登録日2015-08-29
公開日2015-10-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Peptide Dimer Structure in an Abeta(1-42) Fibril Visualized with Cryo-Em
Proc.Natl.Acad.Sci.USA, 112, 2015
2NAO
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BU of 2nao by Molmil
Atomic resolution structure of a disease-relevant Abeta(1-42) amyloid fibril
分子名称: Beta-amyloid protein 42
著者Waelti, M.A, Ravotti, F, Arai, H, Glabe, C, Wall, J, Bockmann, A, Guntert, P, Meier, B.H, Riek, R.
登録日2016-01-07
公開日2016-07-27
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Atomic-resolution structure of a disease-relevant A beta (1-42) amyloid fibril.
Proc.Natl.Acad.Sci.USA, 113, 2016
5HOX
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BU of 5hox by Molmil
X-ray crystallographic structure of an A-beta 17_36 beta-hairpin. Synchrotron data set. (LVFFAEDCGSNKCAII(SAR)LMV).
分子名称: Amyloid beta A4 protein, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500)
著者Kreutzer, A.G, Nowick, J.S, Spencer, R.K.
登録日2016-01-19
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献X-ray Crystallographic Structures of a Trimer, Dodecamer, and Annular Pore Formed by an A beta 17-36 beta-Hairpin.
J.Am.Chem.Soc., 138, 2016
5HOW
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BU of 5how by Molmil
X-ray crystallographic structure of an Abeta 17-36 beta-hairpin. LV(PHI)FAEDCGSNKCAII(SAR)L(ORN)V
分子名称: Amyloid beta A4 protein
著者Kreutzer, A.G, Nowick, J.S, Spencer, R.K.
登録日2016-01-19
公開日2016-03-23
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.295 Å)
主引用文献X-ray Crystallographic Structures of a Trimer, Dodecamer, and Annular Pore Formed by an A beta 17-36 beta-Hairpin.
J.Am.Chem.Soc., 138, 2016
5HOY
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BU of 5hoy by Molmil
X-ray crystallographic structure of an A-beta 17_36 beta-hairpin. X-ray diffractometer data set. (LVFFAEDCGSNKCAII(SAR)LMV).
分子名称: Amyloid beta A4 protein, O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500)
著者Kreutzer, A.G, Spencer, R.K, Nowick, J.S.
登録日2016-01-19
公開日2016-03-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.295 Å)
主引用文献X-ray Crystallographic Structures of a Trimer, Dodecamer, and Annular Pore Formed by an A beta 17-36 beta-Hairpin.
J.Am.Chem.Soc., 138, 2016
5KK3
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BU of 5kk3 by Molmil
Atomic Resolution Structure of Monomorphic AB42 Amyloid Fibrils
分子名称: Beta-amyloid protein 42
著者Colvin, M.T, Silvers, R, Zhe Ni, Q, Can, T.V, Sergeyev, I, Rosay, M, Donovan, K.J, Michael, B, Wall, J, Linse, S, Griffin, R.G.
登録日2016-06-20
公開日2016-07-13
最終更新日2024-05-01
実験手法SOLID-STATE NMR
主引用文献Atomic Resolution Structure of Monomorphic A beta 42 Amyloid Fibrils.
J.Am.Chem.Soc., 138, 2016

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件を2024-05-29に公開中

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