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6DUY
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BU of 6duy by Molmil
Crystal structure of the alpha-N-catenin actin-binding domain H1 mutant
分子名称: Catenin alpha-2
著者Ishiyama, N, Ikura, M.
登録日2018-06-22
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions.
Nat Commun, 9, 2018
4DJ9
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BU of 4dj9 by Molmil
Human vinculin head domain Vh1 (residues 1-258) in complex with the talin vinculin binding site 50 (VBS50, residues 2078-2099)
分子名称: Talin-1, Vinculin
著者Yogesha, S.D, Rangarajan, E.S, Vonrhein, C, Bricogne, G, Izard, T.
登録日2012-02-01
公開日2012-02-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of vinculin in complex with vinculin binding site 50 (VBS50), the integrin binding site 2 (IBS2) of talin.
Protein Sci., 21, 2012
5L0G
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BU of 5l0g by Molmil
Human metavinculin MVt Q971R, R975D, T978R mutant (residues 959-1134) in complex with PIP2
分子名称: Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Chinthalapudi, K, Izard, T.
登録日2016-07-27
公開日2016-08-31
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization.
Proc.Natl.Acad.Sci.USA, 113, 2016
5L0D
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BU of 5l0d by Molmil
Human Metavinculin(residues 959-1130) in complex with PIP2
分子名称: Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Chinthalapudi, K, Izard, T.
登録日2016-07-27
公開日2016-08-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Differential lipid binding of vinculin isoforms promotes quasi-equivalent dimerization.
Proc.Natl.Acad.Sci.USA, 113, 2016
3S90
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BU of 3s90 by Molmil
Human vinculin head domain Vh1 (residues 1-252) in complex with murine talin (VBS33; residues 1512-1546)
分子名称: Talin-1, Vinculin
著者Yogesha, S.D, Sharff, A, Bricogne, G, Izard, T.
登録日2011-05-31
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Intermolecular versus intramolecular interactions of the vinculin binding site 33 of talin.
Protein Sci., 20, 2011
4E17
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BU of 4e17 by Molmil
Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin
分子名称: Catenin alpha-1, Vinculin
著者Choi, H.-J, Pokutta, S, Cadwell, G.W, Bankston, L.A, Liddington, R.C, Weis, W.I.
登録日2012-03-05
公開日2012-05-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.304 Å)
主引用文献Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin
To be Published
6FQ4
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BU of 6fq4 by Molmil
Structure of Chlamydial virulence factor TarP and vinculin head domain
分子名称: TarP-VBS1, Vinculin
著者Whitewood, A.J, Singh, A.K, Brown, D.G, Goult, B.T.
登録日2018-02-13
公開日2018-05-09
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Chlamydial virulence factor TarP mimics talin to disrupt the talin-vinculin complex.
FEBS Lett., 592, 2018
7KTU
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BU of 7ktu by Molmil
Cryogenic electron microscopy model of full-length human metavinculin H1'-parallel conformation 1
分子名称: metavinculin
著者Izard, T, Rangarajan, E.S.
登録日2020-11-24
公開日2021-01-27
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.15 Å)
主引用文献The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain.
Int J Mol Sci, 22, 2021
7KTV
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BU of 7ktv by Molmil
Cryogenic electron microscopy model of full-length human metavinculin H1' kinked conformation
分子名称: metavinculin
著者Izard, T, Rangarajan, E.S.
登録日2020-11-24
公開日2021-01-27
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain.
Int J Mol Sci, 22, 2021
6FUY
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BU of 6fuy by Molmil
Crystal structure of human full-length vinculin-T12-A974K (residues 1-1066)
分子名称: CALCIUM ION, Vinculin
著者Chorev, D.S, Volberg, T, Livne, A, Eisenstein, M, Martins, B, Kam, Z, Jockusch, B.M, Medalia, O, Sharon, M, Geiger, B.
登録日2018-02-28
公開日2018-03-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Conformational states during vinculin unlocking differentially regulate focal adhesion properties.
Sci Rep, 8, 2018
7KTW
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BU of 7ktw by Molmil
Cryogenic electron microscopy model of full-length human metavinculin H1'-parallel conformation 2
分子名称: metavinculin
著者Izard, T, Rangarajan, E.S.
登録日2020-11-24
公開日2021-01-27
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.27 Å)
主引用文献The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain.
Int J Mol Sci, 22, 2021
7KTT
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BU of 7ktt by Molmil
Cryogenic electron microscopy model of full-length human metavinculin
分子名称: metavinculin
著者Izard, T, Rangarajan, E.S.
登録日2020-11-24
公開日2021-01-27
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.17 Å)
主引用文献The Cryogenic Electron Microscopy Structure of the Cell Adhesion Regulator Metavinculin Reveals an Isoform-Specific Kinked Helix in Its Cytoskeleton Binding Domain.
Int J Mol Sci, 22, 2021
4EHP
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BU of 4ehp by Molmil
Crystal Structure of human vinculin head domain (residues 1-252) in complex with alpha-catenin (residues 277-382)
分子名称: ACETATE ION, Catenin alpha-1, Vinculin
著者Izard, T, Rangarajan, E.S.
登録日2012-04-03
公開日2012-04-18
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献alpha-Catenin unfurls upon binding to vinculin
J.Biol.Chem., 287, 2012
3TJ5
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BU of 3tj5 by Molmil
human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-N; residues 412-434) from Rickettsia rickettsii
分子名称: Antigenic heat-stable 120 kDa protein, GLYCEROL, Vinculin
著者Park, H, Lee, J.H, Gouin, E, Cossart, P, Izard, T.
登録日2011-08-23
公開日2011-09-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
J.Biol.Chem., 286, 2011
6DUW
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BU of 6duw by Molmil
Crystal structure of the alpha-N-catenin actin-binding domain H1 mutant
分子名称: Catenin alpha-2
著者Ishiyama, N, Ikura, M.
登録日2018-06-22
公開日2018-12-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions.
Nat Commun, 9, 2018
4E18
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BU of 4e18 by Molmil
Alpha-E-catenin is an autoinhibited molecule that co-activates vinculin
分子名称: Catenin alpha-1, Vinculin
著者Choi, H.-J, Pokutta, S, Cadwell, G.W, Bankston, L.A, Liddington, R.C, Weis, W.I.
登録日2012-03-05
公開日2012-05-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.403 Å)
主引用文献Conformational plasticity of alpha-catenin revealed by binding interactions with vinculin
To be Published
3TJ6
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BU of 3tj6 by Molmil
human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-C; residues 812-835) from Rickettsia rickettsii
分子名称: Antigenic heat-stable 120 kDa protein, Vinculin
著者Park, H, Lee, J.H, Gouin, E, Cossart, P, Izard, T.
登録日2011-08-23
公開日2011-09-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
J.Biol.Chem., 286, 2011
1TR2
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BU of 1tr2 by Molmil
Crystal structure of human full-length vinculin (residues 1-1066)
分子名称: VINCULIN ISOFORM 1
著者Borgon, R.A, Vonrhein, C, Bricogne, G, Bois, P.R, Izard, T.
登録日2004-06-19
公開日2005-11-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure of Human Vinculin
Structure, 12, 2004
1U6H
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BU of 1u6h by Molmil
Vinculin head (0-258) in complex with the talin vinculin binding site 2 (849-879)
分子名称: Talin, Vinculin
著者Fillingham, I, Gingras, A.R, Papagrigoriou, E, Patel, B, Emsley, J, Roberts, G.C.K, Critchley, D.R, Barsukov, I.L.
登録日2004-07-30
公開日2005-01-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献A vinculin binding domain from the talin rod unfolds to form a complex with the vinculin head.
Structure, 13, 2005
1ZW3
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BU of 1zw3 by Molmil
Vinculin Head (0-258) in Complex with the Talin Rod residues 1630-1652
分子名称: Talin 1, Vinculin
著者Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J.
登録日2005-06-03
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
1ZVZ
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BU of 1zvz by Molmil
Vinculin Head (0-258) in Complex with the Talin Rod Residue 820-844
分子名称: Talin 1, Vinculin
著者Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J.
登録日2005-06-03
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
1ZW2
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BU of 1zw2 by Molmil
Vinculin Head (0-258) in Complex with the Talin Rod residues 2345-2369
分子名称: Vinculin, talin
著者Gingras, A.R, Ziegler, W.H, Barsukov, I.L, Roberts, G.C, Critchley, D.R, Emsley, J.
登録日2005-06-03
公開日2005-09-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod
J.Biol.Chem., 280, 2005
1T01
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BU of 1t01 by Molmil
Vinculin complexed with the VBS1 helix from talin
分子名称: Talin 1, unnamed protein product
著者Papagrigoriou, E, Gingras, A.R, Barsukov, I.L, Critchley, D.R, Emsley, J.
登録日2004-04-07
公開日2004-08-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle
Embo J., 23, 2004
1XWJ
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BU of 1xwj by Molmil
Vinculin head (1-258) in complex with the talin vinculin binding site 3 (1945-1969)
分子名称: Talin, Vinculin
著者Gingras, A.R, Papagrigoriou, E, Barsukov, I.L, Critchley, D.R, Emsley, J.
登録日2004-11-01
公開日2005-10-11
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and Dynamic Characterization of a Vinculin Binding Site in the Talin Rod
Biochemistry, 45, 2006
1ST6
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BU of 1st6 by Molmil
Crystal structure of a cytoskeletal protein
分子名称: Vinculin
著者Bakolitsa, C, Liddington, R.C.
登録日2004-03-25
公開日2004-08-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for vinculin activation at sites of cell adhesion.
Nature, 430, 2004

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