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6NHP
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Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin HA2 I45T mutant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Wu, N.C, Wilson, I.A.
登録日2018-12-23
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses.
Science, 368, 2020
6OI0
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BU of 6oi0 by Molmil
Crystal structure of human WDR5 in complex with L-arginine
分子名称: ARGININE, GLYCEROL, SULFATE ION, ...
著者Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D.
登録日2019-04-08
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5.
Biochemistry, 59, 2020
3JVK
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BU of 3jvk by Molmil
Crystal structure of bromodomain 1 of mouse Brd4 in complex with histone H3-K(ac)14
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, histone H3.3 peptide
著者Vollmuth, F, Blankenfeldt, W, Geyer, M.
登録日2009-09-17
公開日2009-10-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution
J.Biol.Chem., 284, 2009
5YJE
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BU of 5yje by Molmil
Crystal structure of HIRA(644-1017)
分子名称: Protein HIRA, SULFATE ION
著者Sato, Y, Senda, M, Senda, T.
登録日2017-10-10
公開日2018-06-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Functional activity of the H3.3 histone chaperone complex HIRA requires trimerization of the HIRA subunit
Nat Commun, 9, 2018
3UEH
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BU of 3ueh by Molmil
Crystal structure of human Survivin H80A mutant
分子名称: 1,2-ETHANEDIOL, Baculoviral IAP repeat-containing protein 5, DI(HYDROXYETHYL)ETHER, ...
著者Niedzialkowska, E, Porebski, P.J, Wang, F, Higgins, J.M, Stukenberg, P.T, Minor, W.
登録日2011-10-30
公開日2012-03-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular basis for phosphospecific recognition of histone H3 tails by Survivin paralogues at inner centromeres.
Mol Biol Cell, 23, 2012
3UIG
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crystal structure of human Survivin in complex with T3 phosphorylated H3(1-15) peptide
分子名称: Baculoviral IAP repeat-containing protein 5, T3 phosphorylated H3(1-15) peptide, ZINC ION
著者Du, J, Patel, D.J.
登録日2011-11-04
公開日2012-02-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human Survivin.
Structure, 20, 2012
2AJ3
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BU of 2aj3 by Molmil
Crystal Structure of a Cross-Reactive HIV-1 Neutralizing CD4-Binding Site Antibody Fab m18
分子名称: Fab m18, Heavy Chain, Light Chain, ...
著者Prabakaran, P, Gan, J, Wu, Y.Q, Zhang, M.Y, Dimitrov, D.S, Ji, X.
登録日2005-08-01
公開日2006-03-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Structural mimicry of CD4 by a cross-reactive HIV-1 neutralizing antibody with CDR-H2 and H3 containing unique motifs.
J.Mol.Biol., 357, 2006
4QQ4
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CW-type zinc finger of MORC3 in complex with the amino terminus of histone H3
分子名称: CHLORIDE ION, Histone H3.3, MORC family CW-type zinc finger protein 3, ...
著者Liu, Y, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2014-06-26
公開日2014-08-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Family-wide Characterization of Histone Binding Abilities of Human CW Domain-containing Proteins.
J.Biol.Chem., 291, 2016
3U5O
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Crystal structure of the complex of TRIM33 PHD-Bromo and H3(1-22)K9me3K14acK18ac histone peptide
分子名称: E3 ubiquitin-protein ligase TRIM33, Histone H3.1, ZINC ION
著者Wang, Z, Patel, D.J.
登録日2011-10-11
公開日2012-01-18
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献A poised chromatin platform for TGF-beta access to master regulators
Cell(Cambridge,Mass.), 147, 2011
2F5K
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BU of 2f5k by Molmil
Crystal structure of the chromo domain of human MRG15
分子名称: Mortality factor 4-like protein 1
著者Zhang, P, Du, J, Ding, J.
登録日2005-11-26
公開日2006-11-14
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of human MRG15 chromo domain and its binding to Lys36-methylated histone H3.
Nucleic Acids Res., 34, 2006
5BT1
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histone chaperone Hif1 playing with histone H2A-H2B dimer
分子名称: HAT1-interacting factor 1, Histone H2A.1, Histone H2B.1
著者Liu, H, Zhang, M, Gao, Y, Teng, M, Niu, L.
登録日2015-06-02
公開日2016-10-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structural Insights into the Association of Hif1 with Histones H2A-H2B Dimer and H3-H4 Tetramer
Structure, 24, 2016
6OFZ
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BU of 6ofz by Molmil
Crystal structure of human WDR5
分子名称: WD repeat-containing protein 5
著者Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D.
登録日2019-04-01
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5.
Biochemistry, 59, 2020
6OI1
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BU of 6oi1 by Molmil
Crystal structure of human WDR5 in complex with monomethyl L-arginine
分子名称: (2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]pentanoic acid, GLYCEROL, SULFATE ION, ...
著者Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D.
登録日2019-04-08
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5.
Biochemistry, 59, 2020
6OI2
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Crystal structure of human WDR5 in complex with symmetric dimethyl-L-arginine
分子名称: GLYCEROL, N3, N4-DIMETHYLARGININE, ...
著者Lorton, B.M, Harijan, R.K, Burgos, E, Bonanno, J.B, Almo, S.C, Shechter, D.
登録日2019-04-08
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5.
Biochemistry, 59, 2020
8I60
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BU of 8i60 by Molmil
Crystal structure of GAS41 YEATS domain in complex with histone H3K27cr
分子名称: ALA-ARG-KCR-SER-ALA-PRO, GLYCEROL, SULFATE ION, ...
著者Konuma, T, Zhou, M.-M.
登録日2023-01-26
公開日2023-07-26
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin.
Mol.Cell, 83, 2023
8CIL
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BU of 8cil by Molmil
Crystal structure of Coxiella burnetii Fic protein 2
分子名称: Fic family protein
著者Hoepfner, D, Itzen, A, Pogenberg, V.
登録日2023-02-10
公開日2023-11-15
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献The DNA-binding induced (de)AMPylation activity of a Coxiella burnetii Fic enzyme targets Histone H3.
Commun Biol, 6, 2023
7ZMX
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BU of 7zmx by Molmil
Crystal structure of the Plant Homeodomain (PHD) of human ING3
分子名称: CALCIUM ION, Inhibitor of growth protein 3, ZINC ION
著者Ferreras, M.O, Medrano, F.J, Blanco, F.J.
登録日2022-04-20
公開日2023-05-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural analysis of ING3 protein and histone H3 binding.
Int.J.Biol.Macromol., 242, 2023
3ASM
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BU of 3asm by Molmil
Crystal structure of Q54A mutant protein of Bst-RNase HIII
分子名称: Ribonuclease HIII
著者Angkawidjaja, C, Kanaya, S.
登録日2010-12-16
公開日2011-06-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.603 Å)
主引用文献Identification of the substrate binding site in the N-terminal TBP-like domain of RNase H3.
Febs Lett., 585, 2011
3O34
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BU of 3o34 by Molmil
Crystal structure of TRIM24 PHD-Bromo complexed with H3(13-32)K23ac peptide
分子名称: BIOTIN, Histone H3.1, Transcription intermediary factor 1-alpha, ...
著者Wang, Z, Patel, D.J.
登録日2010-07-23
公開日2010-12-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献TRIM24 links a non-canonical histone signature to breast cancer.
Nature, 468, 2010
5SZC
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Structure of human Dpf3 double-PHD domain bound to histone H3 tail peptide with monomethylated K4 and acetylated K14
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Histone H3 tail peptide, ZINC ION, ...
著者Singh, N, Local, A, Shiau, A, Ren, B, Corbett, K.D.
登録日2016-08-13
公開日2017-08-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.193 Å)
主引用文献Identification of H3K4me1-associated proteins at mammalian enhancers.
Nat. Genet., 50, 2018
2J8A
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BU of 2j8a by Molmil
X-ray structure of the N-terminus RRM domain of Set1
分子名称: HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-4 SPECIFIC
著者Tresaugues, L, Dehe, P.M, Guerois, R, Rodriguez-Gil, A, Varlet, I, Salah, P, Pamblanco, M, Luciano, P, Quevillon-Cheruel, S, Sollier, J, Leulliot, N, Couprie, J, Tordera, V, Zinn-Justin, S, Chavez, S, Van Tilbeurgh, H, Geli, V.
登録日2006-10-24
公開日2007-03-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-Ray Structure of the N-Terminus Rrm Domain of Set1
To be Published
4O62
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CW-type zinc finger of ZCWPW2 in complex with the amino terminus of histone H3
分子名称: Histone H3.3, UNKNOWN ATOM OR ION, ZINC ION, ...
著者Liu, Y, Tempel, W, Dong, A, Loppnau, P, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2013-12-20
公開日2014-03-26
最終更新日2016-06-08
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Family-wide Characterization of Histone Binding Abilities of Human CW Domain-containing Proteins.
J.Biol.Chem., 291, 2016
1QSR
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BU of 1qsr by Molmil
CRYSTAL STRUCTURE OF TETRAHYMENA GCN5 WITH BOUND ACETYL-COENZYME A
分子名称: ACETYL COENZYME *A, TGCN5 HISTONE ACETYL TRANSFERASE
著者Rojas, J.R, Trievel, R.C, Zhou, J, Mo, Y, Li, X, Berger, S.L, David Allis, C, Marmorstein, R.
登録日1999-06-23
公開日1999-09-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide.
Nature, 401, 1999
1QST
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CRYSTAL STRUCTURE OF TETRAHYMENA GCN5
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, TGCN5 HISTONE ACETYL TRANSFERASE
著者Rojas, J.R, Trievel, R.C, Zhou, J, Mo, Y, Li, X, Berger, S.L, David Allis, C, Marmorstein, R.
登録日1999-06-23
公開日1999-09-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide.
Nature, 401, 1999
7VRF
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Crystal structure of Oxpecker chromodomain in complex with H3K9me3
分子名称: H3K9me3, Oxpecker
著者Huang, Y, Jin, Z, Yu, B.
登録日2021-10-22
公開日2022-10-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural insights into the chromodomain of Oxpecker in complex with histone H3 lysine 9 trimethylation reveal a transposon silencing mechanism by heterodimerization.
Biochem.Biophys.Res.Commun., 652, 2023

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