crystal structure of human Survivin in complex with T3 phosphorylated H3(1-15) peptide

Summary for 3UIG

Related3UIH 3UII 3UIJ 3UIK
DescriptorBaculoviral IAP repeat-containing protein 5, T3 phosphorylated H3(1-15) peptide, ZINC ION, ... (4 entities in total)
Functional Keywordsbir domain, mitosis, t3 phosphorylated h3 binding, smac/diablo binding, phosphorylation, apoptosis-apoptosis inhibitor complex, apoptosis/apoptosis inhibitor
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm O15392
Total number of polymer chains4
Total molecular weight36365.95
Du, J.,Patel, D.J. (deposition date: 2011-11-04, release date: 2012-02-01, Last modification date: 2013-04-24)
Primary citation
Du, J.,Kelly, A.E.,Funabiki, H.,Patel, D.J.
Structural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human Survivin.
Structure, 20:185-195, 2012
PubMed: 22244766 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2011.12.001
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.246280.4%11.9%2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report