3UIK
crystal structure of human Survivin mutant K62Y/H80W in complex with H3(1-10) peptide
Summary for 3UIK
Entry DOI | 10.2210/pdb3uik/pdb |
Related | 3UIG 3UIH 3UII 3UIJ |
Descriptor | Baculoviral IAP repeat-containing protein 5, histone H3(1-10) peptide, ZINC ION (3 entities in total) |
Functional Keywords | bir domain, mitosis, t3 phosphorylated h3 binding, smac/diablo binding, apoptosis-apoptosis inhibitor complex, apoptosis/apoptosis inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: O15392 |
Total number of polymer chains | 4 |
Total formula weight | 35539.17 |
Authors | Du, J.,Patel, D.J. (deposition date: 2011-11-04, release date: 2012-02-01, Last modification date: 2023-09-13) |
Primary citation | Du, J.,Kelly, A.E.,Funabiki, H.,Patel, D.J. Structural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human Survivin. Structure, 20:185-195, 2012 Cited by PubMed: 22244766DOI: 10.1016/j.str.2011.12.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.701 Å) |
Structure validation
Download full validation report