6OFZ
Crystal structure of human WDR5
Summary for 6OFZ
| Entry DOI | 10.2210/pdb6ofz/pdb |
| Descriptor | WD repeat-containing protein 5 (2 entities in total) |
| Functional Keywords | methylation, epigenetics, post-translational modification, chromatin, methylarginine, gene regulation |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 34390.99 |
| Authors | Lorton, B.M.,Harijan, R.K.,Burgos, E.,Bonanno, J.B.,Almo, S.C.,Shechter, D. (deposition date: 2019-04-01, release date: 2020-04-01, Last modification date: 2023-10-11) |
| Primary citation | Lorton, B.M.,Harijan, R.K.,Burgos, E.S.,Bonanno, J.B.,Almo, S.C.,Shechter, D. A Binary Arginine Methylation Switch on Histone H3 Arginine 2 Regulates Its Interaction with WDR5. Biochemistry, 59:3696-3708, 2020 Cited by PubMed: 32207970DOI: 10.1021/acs.biochem.0c00035 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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