1Q6V
 
 | | First crystal structure of a C49 monomer PLA2 from the venom of Daboia russelli pulchella at 1.8 A resolution | | Descriptor: | Phospholipase A2 VRV-PL-VIIIa, SULFATE ION | | Authors: | Singh, N, Pal, A, Jabeen, T, Sharma, S, Singh, T.P. | | Deposit date: | 2003-08-14 | | Release date: | 2004-05-04 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | First crystal structure of a C49 PLA2 from the venom of Daboia russelli pulchella at 1.8A resolution
To be Published
|
|
1ZYX
 | | Crystal structure of the complex of a group IIA phospholipase A2 with a synthetic anti-inflammatory agent licofelone at 1.9A resolution | | Descriptor: | Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, [6-(4-CHLOROPHENYL)-2,2-DIMETHYL-7-PHENYL-2,3-DIHYDRO-1H-PYRROLIZIN-5-YL]ACETIC ACID | | Authors: | Singh, N, Jabeen, T, Sharma, S, Bhushan, A, Singh, T.P. | | Deposit date: | 2005-06-13 | | Release date: | 2005-06-28 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Crystal structure of the complex of a group IIA phospholipase A2 with a synthetic anti-inflammatory agent licofelone at 1.9A resolution
To be Published
|
|
2ARM
 | | Crystal Structure of the Complex of Phospholipase A2 with a natural compound atropine at 1.2 A resolution | | Descriptor: | (1R,5S)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL (2R)-3-HYDROXY-2-PHENYLPROPANOATE, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION | | Authors: | Singh, N, Pal, A, Jabeen, T, Sharma, S, Perbandt, M, Betzel, C, Singh, T.P. | | Deposit date: | 2005-08-20 | | Release date: | 2005-09-20 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.23 Å) | | Cite: | Crystal structures of the complexes of a group IIA phospholipase A2 with two natural anti-inflammatory agents, anisic acid, and atropine reveal a similar mode of binding
Proteins, 64, 2006
|
|
3H1X
 | | Simultaneous inhibition of anti-coagulation and inflammation: Crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand binding site | | Descriptor: | INDOMETHACIN, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION | | Authors: | Singh, N, Prem Kumar, R, Sharma, S, Kaur, P, Singh, T.P. | | Deposit date: | 2009-04-14 | | Release date: | 2009-06-09 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Simultaneous inhibition of anti-coagulation and inflammation: crystal structure of phospholipase A2 complexed with indomethacin at 1.4 A resolution reveals the presence of the new common ligand-binding site
J.Mol.Recognit., 22, 2009
|
|
3G8F
 | | Crystal structure of the complex formed between a group II phospholipase A2 and designed peptide inhibitor carbobenzoxy-dehydro-val-ala-arg-ser at 1.2 A resolution | | Descriptor: | PHQ VAL ALA ARG SER peptide, Phospholipase A2 VRV-PL-VIIIa, SULFATE ION | | Authors: | Singh, N, Kaur, P, Prem Kumar, R, Somvanshi, R.K, Perbandt, M, Betzel, C, Dey, S, Sharma, S, Singh, T.P. | | Deposit date: | 2009-02-12 | | Release date: | 2009-03-10 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Crystal Structure of the Complex Formed between a Group II Phospholipase A2 and Designed Peptide Inhibitor Carbobenzoxy-Dehydro-Val-Ala-Arg-Ser at 1.2 A Resolution
To be Published
|
|
5SZC
 | | Structure of human Dpf3 double-PHD domain bound to histone H3 tail peptide with monomethylated K4 and acetylated K14 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Histone H3 tail peptide, ZINC ION, ... | | Authors: | Singh, N, Local, A, Shiau, A, Ren, B, Corbett, K.D. | | Deposit date: | 2016-08-13 | | Release date: | 2017-08-16 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.193 Å) | | Cite: | Identification of H3K4me1-associated proteins at mammalian enhancers.
Nat. Genet., 50, 2018
|
|
5SZB
 | | Structure of human Dpf3 double-PHD domain bound to histone H3 tail peptide with acetylated K14 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Histone H3 tail peptide, ZINC ION, ... | | Authors: | Singh, N, Local, A, Shiau, A, Ren, B, Corbett, K.D. | | Deposit date: | 2016-08-13 | | Release date: | 2017-08-16 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Identification of H3K4me1-associated proteins at mammalian enhancers.
Nat. Genet., 50, 2018
|
|
6MJB
 | |
4WNL
 | | The X-ray structure of a RNA-binding protein complex | | Descriptor: | GLYCEROL, ISOPROPYL ALCOHOL, SULFATE ION, ... | | Authors: | Singh, N, Blobel, G, Shi, H. | | Deposit date: | 2014-10-13 | | Release date: | 2014-12-24 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Hooking She3p onto She2p for myosin-mediated cytoplasmic mRNA transport.
Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
3KTF
 | |
1OYO
 | | Regulation of protease activity by melanin: Crystal structure of the complex formed between proteinase K and melanin monomers at 2.0 resolution | | Descriptor: | 3H-INDOLE-5,6-DIOL, CALCIUM ION, Proteinase K | | Authors: | Singh, N, Sharma, S, Kumar, S, Raman, G, Singh, T.P. | | Deposit date: | 2003-04-06 | | Release date: | 2003-05-20 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Regulation of protease activity by melanin: Crystal structure of the complex formed between proteinase K and melanin monomers at 2.0 resolution
To be Published
|
|
1OYF
 | | Crystal Structure of Russelles viper (Daboia russellii pulchella) phospholipase A2 in a complex with venom 6-methyl heptanol | | Descriptor: | 6-METHYLHEPTAN-1-OL, ACETIC ACID, Phospholipase A2, ... | | Authors: | Singh, N, Jabeen, T, Sharma, S, Singh, T.P. | | Deposit date: | 2003-04-04 | | Release date: | 2003-05-20 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Crystal Structure of Russelles viper (Daboia russellii pulchella) phospholipase A2 in a complex with venom 6-methyl heptanol
To be Published
|
|
1OXG
 | | Crystal structure of a complex formed between organic solvent treated bovine alpha-chymotrypsin and its autocatalytically produced highly potent 14-residue peptide at 2.2 resolution | | Descriptor: | Chymotrypsinogen A, SULFATE ION | | Authors: | Singh, N, Jabeen, T, Sharma, S, Roy, I, Gupta, M.N, Bilgrami, S, Singh, T.P. | | Deposit date: | 2003-04-02 | | Release date: | 2004-05-18 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Detection of native peptides as potent inhibitors of enzymes. Crystal structure of the complex formed between treated bovine alpha-chymotrypsin and an autocatalytically produced fragment, IIe-Val-Asn-Gly-Glu-Glu-Ala-Val-Pro-Gly-Ser-Trp-Pro-Trp, at 2.2 angstroms resolution.
Febs J., 272, 2005
|
|
1Q7A
 | | Crystal structure of the complex formed between russell's viper phospholipase A2 and an antiinflammatory agent oxyphenbutazone at 1.6A resolution | | Descriptor: | 4-BUTYL-1-(4-HYDROXYPHENYL)-2-PHENYLPYRAZOLIDINE-3,5-DIONE, METHANOL, Phospholipase A2 VRV-PL-VIIIa, ... | | Authors: | Singh, N, Jabeen, T, Sharma, S, Singh, T.P. | | Deposit date: | 2003-08-17 | | Release date: | 2004-05-11 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Phospholipase A2 as a target protein for nonsteroidal anti-inflammatory drugs (NSAIDS): crystal structure of the complex formed between phospholipase A2 and oxyphenbutazone at 1.6 A resolution.
Biochemistry, 43, 2004
|
|
7RK7
 | | The complex between TIL 1383i TCR and human Class I MHC HLA-A2 with the bound Tyrosinase(369-377)(N371D) nonameric peptide | | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A alpha chain, ... | | Authors: | Singh, N.K, Davancaze, L.M, Arbuiso, A, Weiss, L.I, Keller, G.L.J, Baker, B.M. | | Deposit date: | 2021-07-22 | | Release date: | 2022-11-02 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.54 Å) | | Cite: | The complex between TIL 1383i TCR and human Class I MHC HLA-A2 with the bound Tyrosinase(369-377)(N371D) nonameric peptide
To Be Published
|
|
4ZDH
 | | Crystal structure of JKA6 TCR | | Descriptor: | Alpha chain of A6 T-cell receptor,T-cell receptor alpha chain C region, Beta chain of JKF6 T-cell receptor,Protein TRBV28 | | Authors: | Singh, N.K, Hossain, M, Baker, B.M. | | Deposit date: | 2015-04-17 | | Release date: | 2016-05-04 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (2.0984 Å) | | Cite: | Crystal structure of JKA6 TCR
To Be Published
|
|
5V1A
 | | Structure of S. cerevisiae Ulp2:Csm1 complex | | Descriptor: | Monopolin complex subunit CSM1, Ubiquitin-like-specific protease 2 | | Authors: | Singh, N, Corbett, K.D. | | Deposit date: | 2017-03-01 | | Release date: | 2017-05-17 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | Recruitment of a SUMO isopeptidase to rDNA stabilizes silencing complexes by opposing SUMO targeted ubiquitin ligase activity.
Genes Dev., 31, 2017
|
|
5V3N
 | | Structure of S. cerevisiae Ulp2-Tof2-Csm1 complex | | Descriptor: | Monopolin complex subunit CSM1, Ulp2p,Topoisomerase 1-associated factor 2 chimera | | Authors: | SIngh, N, Corbett, K.D. | | Deposit date: | 2017-03-07 | | Release date: | 2017-05-17 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Recruitment of a SUMO isopeptidase to rDNA stabilizes silencing complexes by opposing SUMO targeted ubiquitin ligase activity.
Genes Dev., 31, 2017
|
|
1Y38
 | | Crystal structure of the complex formed between phospholipase A2 dimer and glycerophosphate at 2.4 A resolution | | Descriptor: | Phospholipase A2 VRV-PL-VIIIa, SN-GLYCEROL-3-PHOSPHATE, SODIUM ION, ... | | Authors: | Singh, N, Jabeen, T, Sharma, S, Singh, T.P. | | Deposit date: | 2004-11-24 | | Release date: | 2005-05-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.44 Å) | | Cite: | Crystal structure of the complex formed between phospholipase A2 dimer and glycerophosphate at 2.4 A resolution
To be Published
|
|
2DP8
 | |
5E9D
 | |
6DEX
 | | Structure of Eremothecium gossypii Shu1:Shu2 complex | | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, MAGNESIUM ION, Suppressor of hydroxyurea sensitivity protein 1, ... | | Authors: | Singh, N, Corbett, K.D. | | Deposit date: | 2018-05-13 | | Release date: | 2018-05-23 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure of Eremothecium gossypii Shu1:Shu2 complex
To Be Published
|
|
2DOJ
 | | Crystal structure of the complex of C-terminal lobe of bovine lactoferrin with adenosine at 2.4 A resolution | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE, CARBONATE ION, ... | | Authors: | Singh, N, Jain, R, Sharma, S, Singh, T.P. | | Deposit date: | 2006-04-30 | | Release date: | 2006-05-23 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the complex of C-terminal lobe of bovine lactoferrin with adenosine at 2.4 A resolution
To be Published
|
|
2ALU
 | | Detection of new binding site in the C-terminal lobe of lactoferrin:Crystal structure of the complex formed between bovine lactoferrin and a tetrasaccharide at 2.1A resolution | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, ... | | Authors: | Singh, N, Jabeen, T, Sharma, S, Bhushan, A, Singh, T.P. | | Deposit date: | 2005-08-08 | | Release date: | 2005-09-20 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Detection of new binding site in the C-terminal lobe of lactoferrin:Crystal structure of the complex formed between bovine lactoferrin and a tetrasaccharide at 2.1A resolution
To be Published
|
|
2AYS
 | | A conserved non-metallic binding site in the C-terminal lobe of lactoferrin: Structure of the complex of C-terminal lobe of bovine lactoferrin with N-acetyl galactosamine at 1.86 A resolution | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, ... | | Authors: | Singh, N, Jabeen, T, Sharma, S, Singh, T.P. | | Deposit date: | 2005-09-08 | | Release date: | 2005-09-20 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | A conserved non-metallic binding site in the C-terminal lobe of lactoferrin: Structure of the complex of C-terminal lobe of bovine lactoferrin with N-acetyl galactosamine at 1.86 A resolution
To be Published
|
|
