1Q7A
Crystal structure of the complex formed between russell's viper phospholipase A2 and an antiinflammatory agent oxyphenbutazone at 1.6A resolution
Summary for 1Q7A
Entry DOI | 10.2210/pdb1q7a/pdb |
Related | 1CL5 1OYF |
Descriptor | Phospholipase A2 VRV-PL-VIIIa, SULFATE ION, 4-BUTYL-1-(4-HYDROXYPHENYL)-2-PHENYLPYRAZOLIDINE-3,5-DIONE, ... (5 entities in total) |
Functional Keywords | phospholipase a2, venom, antiinflammatory compound, hydrolase |
Biological source | Daboia russellii pulchella |
Cellular location | Secreted: P59071 |
Total number of polymer chains | 1 |
Total formula weight | 14178.31 |
Authors | Singh, N.,Jabeen, T.,Sharma, S.,Singh, T.P. (deposition date: 2003-08-17, release date: 2004-05-11, Last modification date: 2023-08-16) |
Primary citation | Singh, N.,Jabeen, T.,Somvanshi, R.K.,Sharma, S.,Dey, S.,Singh, T.P. Phospholipase A2 as a target protein for nonsteroidal anti-inflammatory drugs (NSAIDS): crystal structure of the complex formed between phospholipase A2 and oxyphenbutazone at 1.6 A resolution. Biochemistry, 43:14577-14583, 2004 Cited by PubMed: 15544328DOI: 10.1021/bi0483561 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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