3U5O

Crystal structure of the complex of TRIM33 PHD-Bromo and H3(1-22)K9me3K14acK18ac histone peptide

Summary for 3U5O

Entry DOI	10.2210/pdb3u5o/pdb
Related	3U5M 3U5N 3U5P
Descriptor	E3 ubiquitin-protein ligase TRIM33, Histone H3.1, ZINC ION (3 entities in total)
Functional Keywords	trim33, phd, bromodomain, tgf-beta, epigenetics, histone, methylation, k9me3, k14ac, k18ac, transcription
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: Q9UPN9 P68431
Total number of polymer chains	16
Total formula weight	211583.78
Authors	Wang, Z.,Patel, D.J. (deposition date: 2011-10-11, release date: 2012-01-18, Last modification date: 2023-12-06)
Primary citation	Xi, Q.,Wang, Z.,Zaromytidou, A.I.,Zhang, X.H.,Chow-Tsang, L.F.,Liu, J.X.,Kim, H.,Barlas, A.,Manova-Todorova, K.,Kaartinen, V.,Studer, L.,Mark, W.,Patel, D.J.,Massague, J. A poised chromatin platform for TGF-beta access to master regulators Cell(Cambridge,Mass.), 147:1511-1524, 2011 Cited by PubMed: 22196728 DOI: 10.1016/j.cell.2011.11.032 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation