6NHP

Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin HA2 I45T mutant

Summary for 6NHP

• Entry DOI: 10.2210/pdb6nhp/pdb
• Descriptor: Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: influenza virus, hemagglutinin, viral protein
• Biological source: Influenza A virus (strain A/Hong Kong/1/1968 H3N2); More
• Total number of polymer chains: 6
• Total formula weight: 171585.83

Authors

Wu, N.C.,Wilson, I.A. (deposition date: 2018-12-23, release date: 2020-04-15, Last modification date: 2023-10-11)

• Primary citation: Wu, N.C.,Thompson, A.J.,Lee, J.M.,Su, W.,Arlian, B.M.,Xie, J.,Lerner, R.A.,Yen, H.L.,Bloom, J.D.,Wilson, I.A.; Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses.; Science, 368:1335-1340, 2020; PubMed: 32554590; DOI: 10.1126/science.aaz5143

Experimental method

X-RAY DIFFRACTION (2.25 Å)