6NHP
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin HA2 I45T mutant
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E | Hemagglutinin HA1 chain | polymer | 321 | 35320.8 | 3 | UniProt (H9XC94) Pfam (PF00509) UniProt (by SIFTS) (Q91MA7) In PDB | Influenza A virus (strain A/Hong Kong/1/1968 H3N2) | |
2 | B, D, F | Hemagglutinin HA2 chain | polymer | 176 | 20185.3 | 3 | UniProt (Q91MA7) Pfam (PF00509) In PDB | Influenza A virus (strain A/Hong Kong/1/1968 H3N2) | |
3 | G, H | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
4 | I, K | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
5 | J | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G22573RC) | |||
6 | L | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
7 | A, C, D, E | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) | |||
8 | water | water | 18.0 | 666 | Chemie (HOH) |
Sequence modifications
A, C, E: 11 - 329 (UniProt: H9XC94)
B, D, F: 1 - 176 (UniProt: Q91MA7)
PDB | External Database | Details |
---|---|---|
Pro 9 | - | expression tag |
Gly 10 | - | expression tag |
Ser 145 | Unk 161 | variant |
Leu 226 | Met 242 | conflict |
PDB | External Database | Details |
---|---|---|
Thr 45 | Ile 390 | engineered mutation |
Gly 123 | Arg 468 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 166518.1 | |
Branched | Number of molecules | 6 |
Total formula weight | 3519.3 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1548.5 | |
All* | Total formula weight | 171585.8 |