7MQY
| Zebrafish CNTN4 APLP2 complex | 分子名称: | Fusion protein of CNTN4 and APLP2 | 著者 | Bouyain, S, Karuppan, S.J. | 登録日 | 2021-05-07 | 公開日 | 2022-01-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface. J.Biol.Chem., 298, 2021
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7MRN
| Mouse CNTN5 APP complex | 分子名称: | Contactin-5, N-APP | 著者 | Bouyain, S, Karuppan, S.J. | 登録日 | 2021-05-07 | 公開日 | 2022-01-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface. J.Biol.Chem., 298, 2021
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7MRS
| Zebrafish CNTN4 APPb complex | 分子名称: | Amyloid-beta A4 protein, Contactin-4 | 著者 | Bouyain, S, Karuppan, S.J. | 登録日 | 2021-05-09 | 公開日 | 2022-01-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | 主引用文献 | Members of the vertebrate contactin and amyloid precursor protein families interact through a conserved interface. J.Biol.Chem., 298, 2021
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1ZLG
| Solution structure of the extracellular matrix protein anosmin-1 | 分子名称: | Anosmin 1 | 著者 | Hu, Y, Sun, Z, Eaton, J.T, Bouloux, P.M, Perkins, S.J. | 登録日 | 2005-05-06 | 公開日 | 2006-05-09 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION SCATTERING | 主引用文献 | Extended and Flexible Domain Solution Structure of the Extracellular Matrix Protein Anosmin-1 by X-ray Scattering, Analytical Ultracentrifugation and Constrained Modelling. J.Mol.Biol., 350, 2005
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7MD4
| Insulin receptor ectodomain dimer complexed with two IRPA-3 partial agonists | 分子名称: | Insulin B chain, Insulin chain A, Isoform Short of Insulin receptor, ... | 著者 | Gomez-Llorente, Y, Zhou, H, Scapin, G. | 登録日 | 2021-04-03 | 公開日 | 2022-02-23 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists. Nat Commun, 13, 2022
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7MD5
| Insulin receptor ectodomain dimer complexed with two IRPA-9 partial agonists | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Gomez-Llorente, Y, Zhou, H, Scapin, G. | 登録日 | 2021-04-03 | 公開日 | 2022-02-23 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | 主引用文献 | Functionally selective signaling and broad metabolic benefits by novel insulin receptor partial agonists. Nat Commun, 13, 2022
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7MQO
| The insulin receptor ectodomain in complex with a venom hybrid insulin analog - "head" region | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, ... | 著者 | Blakely, A.D, Xiong, X, Kim, J.H, Menting, J, Schafer, I.B, Schubert, H.L, Agrawal, R, Gutmann, T, Delaine, C, Zhang, Y, Artik, G.O, Merriman, A, Eckert, D, Lawrence, M.C, Coskun, U, Fisher, S.J, Forbes, B.E, Safavi-Hemami, H, Hill, C.P, Chou, D.H.C. | 登録日 | 2021-05-06 | 公開日 | 2022-03-16 | 最終更新日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Symmetric and asymmetric receptor conformation continuum induced by a new insulin. Nat.Chem.Biol., 18, 2022
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7MQR
| The insulin receptor ectodomain in complex with four venom hybrid insulins - symmetric conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ... | 著者 | Blakely, A.D, Xiong, X, Kim, J.H, Menting, J, Schafer, I.B, Schubert, H.L, Agrawal, R, Gutmann, T, Delaine, C, Zhang, Y, Artik, G.O, Merriman, A, Eckert, D, Lawrence, M.C, Coskun, U, Fisher, S.J, Forbes, B.E, Safavi-Hemami, H, Hill, C.P, Chou, D.H.C. | 登録日 | 2021-05-06 | 公開日 | 2022-03-16 | 最終更新日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Symmetric and asymmetric receptor conformation continuum induced by a new insulin. Nat.Chem.Biol., 18, 2022
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3MTR
| Crystal structure of the Ig5-FN1 tandem of human NCAM | 分子名称: | Neural cell adhesion molecule 1, SULFATE ION | 著者 | Lavie, A, Foley, D.A. | 登録日 | 2010-04-30 | 公開日 | 2010-06-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure and mutagenesis of neural cell adhesion molecule domains: evidence for flexibility in the placement of polysialic acid attachment sites J.Biol.Chem., 285, 2010
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3MX0
| Crystal Structure of EphA2 ectodomain in complex with ephrin-A5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 2, ... | 著者 | Himanen, J.P, Yermekbayeva, L, Janes, P.W, Walker, J.R, Xu, K, Atapattu, L, Rajashankar, K.R, Mensinga, A, Lackmann, M, Nikolov, D.B, Dhe-Paganon, S. | 登録日 | 2010-05-06 | 公開日 | 2010-06-30 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.506 Å) | 主引用文献 | Architecture of Eph receptor clusters. Proc.Natl.Acad.Sci.USA, 107, 2010
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3N1G
| Crystal structure of DhhN bound to BOCFn3 | 分子名称: | Brother of CDO, CALCIUM ION, Desert hedgehog protein, ... | 著者 | Kavran, J.M, Leahy, D.J. | 登録日 | 2010-05-15 | 公開日 | 2010-06-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285, 2010
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3N1P
| Crystal Structure of IhhN bound to BOCFn3 | 分子名称: | Brother of CDO, CALCIUM ION, Indian hedgehog protein, ... | 著者 | Kavran, J.M, Leahy, D.J. | 登録日 | 2010-05-16 | 公開日 | 2010-06-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285, 2010
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7NWL
| Cryo-EM structure of human integrin alpha5beta1 (open form) in complex with fibronectin and TS2/16 Fv-clasp | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin alpha-5, ... | 著者 | Schumacher, S, Dedden, D, Vazquez Nunez, R, Matoba, K, Takagi, J, Biertumpfel, C, Mizuno, N. | 登録日 | 2021-03-17 | 公開日 | 2021-06-02 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into integrin alpha 5 beta 1 opening by fibronectin ligand. Sci Adv, 7, 2021
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3N1Q
| Crystal Structure of DhhN bound to CDOFn3 | 分子名称: | CALCIUM ION, Cell adhesion molecule-related/down-regulated by oncogenes, Desert hedgehog protein, ... | 著者 | Kavran, J.M, Leahy, D.J. | 登録日 | 2010-05-16 | 公開日 | 2010-06-02 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285, 2010
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3N1F
| Crystal Structure of IhhN bound to CDOFn3 | 分子名称: | CALCIUM ION, Cell adhesion molecule-related/down-regulated by oncogenes, Indian hedgehog protein, ... | 著者 | Kavran, J.M, Leahy, D.J. | 登録日 | 2010-05-15 | 公開日 | 2010-06-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285, 2010
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3N1M
| Crystal Structure of IhhN bound to BOCFn3 | 分子名称: | Brother of CDO, CALCIUM ION, Indian hedgehog protein, ... | 著者 | Kavran, J.M, Leahy, D.J. | 登録日 | 2010-05-15 | 公開日 | 2010-06-02 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J.Biol.Chem., 285, 2010
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2AEW
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8K53
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8OE4
| Cryo-EM structure of a pre-dimerized human IL-23 complete extracellular signaling complex. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, ... | 著者 | Bloch, Y, Felix, J, Savvides, S.N. | 登録日 | 2023-03-10 | 公開日 | 2024-02-07 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23. Nat.Struct.Mol.Biol., 31, 2024
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8ODZ
| Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class 1). | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, Interleukin-12 receptor subunit beta-2,Calmodulin-1, ... | 著者 | Felix, J, Bloch, Y, Savvides, S.N. | 登録日 | 2023-03-10 | 公開日 | 2024-02-07 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23. Nat.Struct.Mol.Biol., 31, 2024
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8OE0
| Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class 2). | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, ... | 著者 | Felix, J, Bloch, Y, Savvides, S.N. | 登録日 | 2023-03-10 | 公開日 | 2024-02-07 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23. Nat.Struct.Mol.Biol., 31, 2024
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8Q6T
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8PB1
| Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class 1), obtained after local refinement. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, Interleukin-12 receptor subunit beta-2,Calmodulin-1, ... | 著者 | Felix, J, Bloch, Y, Savvides, S.N. | 登録日 | 2023-06-08 | 公開日 | 2024-02-07 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23. Nat.Struct.Mol.Biol., 31, 2024
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8D74
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8D82
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