4MMY
Integrin AlphaVBeta3 ectodomain bound to the tenth domain of Fibronectin with the IAKGDWND motif
Summary for 4MMY
Entry DOI | 10.2210/pdb4mmy/pdb |
Related | 1JV2 1L5G 3IJE 4G1E 4G1M 4MMX 4MMZ |
Descriptor | Integrin alpha-V, Integrin beta-3, Fibronectin, ... (10 entities in total) |
Functional Keywords | integrin, a domain, hybrid domain, psi, egf repeats, beta ta thigh, beta propeller, rgd motif, fibronectin, vitronectin, cell adhesion |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 200063.80 |
Authors | van Agthoven, J.,Xiong, J.,Arnaout, M.A. (deposition date: 2013-09-09, release date: 2014-03-26, Last modification date: 2020-07-29) |
Primary citation | Van Agthoven, J.F.,Xiong, J.P.,Alonso, J.L.,Rui, X.,Adair, B.D.,Goodman, S.L.,Arnaout, M.A. Structural basis for pure antagonism of integrin alpha V beta 3 by a high-affinity form of fibronectin. Nat.Struct.Mol.Biol., 21:383-388, 2014 Cited by PubMed: 24658351DOI: 10.1038/nsmb.2797 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.183 Å) |
Structure validation
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