3IJE

Crystal structure of the complete integrin alhaVbeta3 ectodomain plus an Alpha/beta transmembrane fragment

Summary for 3IJE

Entry DOI	10.2210/pdb3ije/pdb
Descriptor	Integrin alpha-V, Integrin beta-3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	integrin structure, activation, egf domains, flim, cell signaling, cell adhesion, cleavage on pair of basic residues, disulfide bond, glycoprotein, host-virus interaction, integrin, membrane, receptor, transmembrane, disease mutation, phosphoprotein, protein binding
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	190868.92
Authors	Xiong, J.-P.,Mahalingham, B.,Rui, X.,Hyman, B.T.,Goodman, S.L.,Arnaout, M.A. (deposition date: 2009-08-04, release date: 2009-09-29, Last modification date: 2023-09-06)
Primary citation	Xiong, J.P.,Mahalingham, B.,Alonso, J.L.,Borrelli, L.A.,Rui, X.,Anand, S.,Hyman, B.T.,Rysiok, T.,Muller-Pompalla, D.,Goodman, S.L.,Arnaout, M.A. Crystal structure of the complete integrin alphaVbeta3 ectodomain plus an alpha/beta transmembrane fragment. J.Cell Biol., 186:589-600, 2009 Cited by PubMed: 19704023 DOI: 10.1083/jcb.200905085 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation