3IJE

Crystal structure of the complete integrin alhaVbeta3 ectodomain plus an Alpha/beta transmembrane fragment

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Integrin alpha-V	polymer	967	106970.6	1	UniProt (P06756) Pfam (PF01839) Pfam (PF08441) Pfam (PF20805) Pfam (PF20806) In PDB	Homo sapiens (human)	Vitronectin receptor subunit alpha, Integrin alpha-V heavy chain, Integrin alpha-V light chain
2	B	Integrin beta-3	polymer	695	76848.6	1	UniProt (P05106) Pfam (PF07974) Pfam (PF07965) Pfam (PF17205) Pfam (PF00362) Pfam (PF18372) In PDB	Homo sapiens (human)	Platelet membrane glycoprotein IIIa, GPIIIa
3	C	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G22768VO)
4	D, F, G, H, I...	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	6	In PDB GlyTouCan (G42666HT)
5	E	alpha-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1073.0	1	In PDB GlyTouCan (G34220DL)
6	J, L	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	2	In PDB GlyTouCan (G15407YE)
7	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)
8	A, B	CALCIUM ION	non-polymer		40.1	6	Chemie (CA)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	183819.1
Branched	Number of molecules	10
	Total formula weight	5703.3
Non-Polymers*	Number of molecules	11
	Total formula weight	1346.5
All*	Total formula weight	190868.9

*Water molecules are not included.