PDB: 425 件ウェブページステータス検索Chemie searchBIRD

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2L14	Structure of CBP nuclear coactivator binding domain in complex with p53 TAD 分子名称: CREB-binding protein, Cellular tumor antigen p53 著者 Lee, C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. 登録日 2010-07-22 公開日 2010-11-03 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structure of the p53 transactivation domain in complex with the nuclear receptor coactivator binding domain of CREB binding protein. Biochemistry, 49, 2010
2L4Z	NMR structure of fusion of CtIP (641-685) to LMO4-LIM1 (18-82) 分子名称: DNA endonuclease RBBP8,LIM domain transcription factor LMO4, ZINC ION 著者 Liew, C, Stokes, P.H, Kwan, A.H, Matthews, J.M. 登録日 2010-10-22 公開日 2011-10-26 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structural Basis of the Interaction of the Breast Cancer Oncogene LMO4 with the Tumour Suppressor CtIP/RBBP8. J.Mol.Biol., 425, 2013
2YT4	Crystal structure of human DGCR8 core 分子名称: Protein DGCR8 著者 Cho, Y, Sohn, S.Y. 登録日 2007-04-05 公開日 2007-08-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of human DGCR8 core Nat.Struct.Mol.Biol., 14, 2007
2RP3	Solution Structure of Cyanovirin-N Domain B Mutant 分子名称: Cyanovirin-N 著者 Matei, E, Furey, W, Gronenborn, A.M. 登録日 2008-04-30 公開日 2008-08-19 最終更新日 2021-11-10 実験手法 SOLUTION NMR 主引用文献 Solution and crystal structures of a sugar binding site mutant of cyanovirin-N: no evidence of domain swapping Structure, 16, 2008
2Z5T	Molecular basis for the inhibition of p53 by Mdmx 分子名称: Cellular tumor antigen p53, Mdm4 protein 著者 Popowicz, G.M, Czarna, A, Rothweiler, U, Szwagierczak, A, Holak, T.A. 登録日 2007-07-17 公開日 2007-11-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular basis for the inhibition of p53 by Mdmx. Cell Cycle, 6, 2007
2U2A	STEM LOOP IIA FROM U2 SNRNA OF SACCHAROMYCES CEREVISIAE, NMR, MINIMIZED AVERAGE STRUCTURE 分子名称: RNA (5'-R(P*GP*GP*UP*CP*AP*GP*UP*GP*UP*AP*AP*CP*AP*AP*CP*UP*GP*AP*CP*C)-3') 著者 Stallings, S.C, Moore, P.B. 登録日 1997-08-20 公開日 1998-03-04 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The structure of an essential splicing element: stem loop IIa from yeast U2 snRNA. Structure, 5, 1997
2VJF	Crystal Structure of the MDM2-MDMX RING Domain Heterodimer 分子名称: CITRATE ANION, E3 UBIQUITIN-PROTEIN LIGASE MDM2, MDM4 PROTEIN, ... 著者 Mace, P.D, Linke, K, Smith, C.A, Day, C.L. 登録日 2007-12-10 公開日 2008-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of the Mdm2/Mdmx Ring Domain Heterodimer Reveals Dimerization is Required for Their Ubiquitylation in Trans. Cell Death Differ., 15, 2008
2VJE	Crystal Structure of the MDM2-MDMX RING Domain Heterodimer 分子名称: CITRATE ANION, E3 UBIQUITIN-PROTEIN LIGASE MDM2, MDM4 PROTEIN, ... 著者 Mace, P.D, Linke, K, Smith, C.A, Day, C.L. 登録日 2007-12-10 公開日 2008-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans. Cell Death Differ., 15, 2008
2W0J	Crystal structure of Chk2 in complex with NSC 109555, a specific inhibitor 分子名称: 4,4'-DIACETYLDIPHENYLUREA-BIS(GUANYLHYDRAZONE), NITRATE ION, SERINE/THREONINE-PROTEIN KINASE CHK2 著者 Lountos, G.T, Tropea, J.E, Zhang, D, Jobson, A.G, Pommier, Y, Shoemaker, R.H, Waugh, D.S. 登録日 2008-08-18 公開日 2009-02-10 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal Structure of Checkpoint Kinase 2 in Complex with Nsc 109555, a Potent and Selective Inhibitor Protein Sci., 18, 2009
3I6W	Structure and Activation Mechanism of the CHK2 DNA-Damage Checkpoint Kinase 分子名称: Serine/threonine-protein kinase Chk2 著者 Pavletich, N.P. 登録日 2009-07-07 公開日 2009-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Structure and activation mechanism of the CHK2 DNA damage checkpoint kinase. Mol.Cell, 35, 2009
3I6U	Structure and Activation Mechanism of the CHK2 DNA-Damage Checkpoint Kinase 分子名称: Serine/threonine-protein kinase Chk2 著者 Pavletich, N.P. 登録日 2009-07-07 公開日 2009-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure and activation mechanism of the CHK2 DNA damage checkpoint kinase. Mol.Cell, 35, 2009
3J9T	Yeast V-ATPase state 1 分子名称: V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... 著者 Zhao, J, Benlekbir, S, Rubinstein, J.L. 登録日 2015-02-23 公開日 2015-05-13 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (6.9 Å) 主引用文献 Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase. Nature, 521, 2015
3J9U	Yeast V-ATPase state 2 分子名称: V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... 著者 Zhao, J, Benlekbir, S, Rubinstein, J.L. 登録日 2015-02-23 公開日 2015-05-13 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (7.6 Å) 主引用文献 Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase. Nature, 521, 2015
3K2L	Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2) 分子名称: CHLORIDE ION, Dual specificity tyrosine-phosphorylation-regulated kinase 2, SODIUM ION, ... 著者 Filippakopoulos, P, Myrianthopoulos, V, Soundararajan, M, Krojer, T, Hapka, E, Fedorov, O, Berridge, G, Wang, J, Shrestha, L, Pike, A.C.W, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Bountra, C, Mikros, E, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2009-09-30 公開日 2009-10-13 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition. Structure, 21, 2013
2XVS	Crystal structure of human TTC5 (Strap) C-terminal OB domain 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, IODIDE ION, ... 著者 Adams, J, Pike, A.C.W, Maniam, S, Sharpe, T.D, Coutts, A.S, Knapp, S, La Thangue, B, Bullock, A.N. 登録日 2010-10-31 公開日 2010-11-17 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The P53 Cofactor Strap Exhibits an Unexpected Tpr Motif and Oligonucleotide-Binding (Ob)-Fold Structure. Proc.Natl.Acad.Sci.USA, 109, 2012
2WTI	CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH AN INHIBITOR 分子名称: 1,2-ETHANEDIOL, 4-[2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-YL)PYRIDIN-3-YL]BENZAMIDE, CHECKPOINT KINASE 2, ... 著者 Hilton, S, Naud, S, Caldwell, J.J, Boxall, K, Burns, S, Anderson, V.E, Antoni, L, Allen, C.E, Pearl, L.H, Oliver, A.W, Aherne, G.W, Garrett, M.D, Collins, I. 登録日 2009-09-16 公開日 2009-12-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Identification and Characterisation of 2-Aminopyridine Inhibitors of Checkpoint Kinase 2 Bioorg.Med.Chem., 18, 2010
3J9V	Yeast V-ATPase state 3 分子名称: V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... 著者 Zhao, J, Benlekbir, S, Rubinstein, J.L. 登録日 2015-02-23 公開日 2015-05-13 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (8.3 Å) 主引用文献 Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase. Nature, 521, 2015
2Z5S	Molecular basis for the inhibition of p53 by Mdmx 分子名称: Cellular tumor antigen p53, Mdm4 protein 著者 Popowicz, G.M, Czarna, A, Rothweiler, U, Szwagierczak, A, Holak, T.A. 登録日 2007-07-17 公開日 2007-11-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular basis for the inhibition of p53 by Mdmx. Cell Cycle, 6, 2007
2WTJ	CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH AN INHIBITOR 分子名称: 1,2-ETHANEDIOL, 2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-YL)-N-[2-(DIMETHYLAMINO)ETHYL]PYRIDINE-3-CARBOXAMIDE, CHECKPOINT KINASE 2, ... 著者 Hilton, S, Naud, S, Caldwell, J.J, Boxall, K, Burns, S, Anderson, V.E, Antoni, L, Allen, C.E, Pearl, L.H, Oliver, A.W, Aherne, G.W, Garrett, M.D, Collins, I. 登録日 2009-09-16 公開日 2009-12-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Identification and Characterisation of 2-Aminopyridine Inhibitors of Checkpoint Kinase 2 Bioorg.Med.Chem., 18, 2010
3BU8	Crystal Structure of TRF2 TRFH domain and TIN2 peptide complex 分子名称: TERF1-interacting nuclear factor 2, Telomeric repeat-binding factor 2 著者 Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M. 登録日 2008-01-02 公開日 2008-02-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins. Science, 319, 2008
3BRV	NEMO/IKKb association domain structure 分子名称: Inhibitor of nuclear factor kappa-B kinase subunit beta, NF-kappa-B essential modulator 著者 Silvian, L.F. 登録日 2007-12-21 公開日 2008-04-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of a NEMO/IKK-Associating Domain Reveals Architecture of the Interaction Site. Structure, 16, 2008
3BUA	Crystal Structure of TRF2 TRFH domain and APOLLO peptide complex 分子名称: DNA cross-link repair 1B protein, Telomeric repeat-binding factor 2 著者 Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M. 登録日 2008-01-02 公開日 2008-02-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins. Science, 319, 2008
1GGW	CDC4P FROM SCHIZOSACCHAROMYCES POMBE 分子名称: PROTEIN (CDC4P) 著者 Slupsky, C.M, Hemmingsen, S.M, McIntosh, L.P. 登録日 2000-09-25 公開日 2001-03-21 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Structure of Cdc4p, a contractile ring protein essential for cytokinesis in Schizosaccharomyces pombe. J.Biol.Chem., 276, 2001
5VOX	Yeast V-ATPase in complex with Legionella pneumophila effector SidK (rotational state 1) 分子名称: V-type proton ATPase catalytic subunit A,V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... 著者 Zhao, J. 登録日 2017-05-03 公開日 2017-06-21 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (6.8 Å) 主引用文献 Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein. PLoS Pathog., 13, 2017
5VZT	Crystal structure of the Skp1-FBXO31 complex 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, F-box only protein 31, PHOSPHATE ION, ... 著者 Li, Y, Jin, K, Hao, B. 登録日 2017-05-29 公開日 2018-01-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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