8CF0

Crystal structure of human DNA cross-link repair 1A in complex with quinoxalinedione inhibitor H2

Summary for 8CF0

• Entry DOI: 10.2210/pdb8cf0/pdb
• Descriptor: DNA cross-link repair 1A protein, DIMETHYL SULFOXIDE, 9-chloranyl-1,4-dihydropyrazino[2,3-c]quinoline-2,3-dione, ... (5 entities in total)
• Functional Keywords: snm1a, nuclease inhibitor, icl, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 39524.80

Authors

Newman, J.A.,Yosaatmadja, Y.,Baddock, H.T.,Bielinski, M.,von Delft, F.,Bountra, C.,McHugh, P.J.,Schofield, C.J.,Gileadi, O. (deposition date: 2023-02-02, release date: 2024-02-21)

• Primary citation: Newman, J.A.,Yosaatmadja, Y.,Baddock, H.T.,Bielinski, M.,von Delft, F.,Bountra, C.,McHugh, P.J.,Schofield, C.J.,Gileadi, O.; Crystal structure of human DNA cross-link repair 1A in complex with quinoxalinedione inhibitor H2; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.76 Å)