8CF0
Crystal structure of human DNA cross-link repair 1A in complex with quinoxalinedione inhibitor H2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA cross-link repair 1A protein | polymer | 345 | 39140.3 | 1 | UniProt (Q6PJP8) Pfam (PF07522) In PDB | Homo sapiens (human) | Beta-lactamase DCLRE1A,SNM1 homolog A,hSNM1,hSNM1A |
| 2 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 3 | A | 9-chloranyl-1,4-dihydropyrazino[2,3-c]quinoline-2,3-dione | non-polymer | 247.6 | 1 | Chemie (UF3) | |||
| 4 | A | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 5 | water | water | 18.0 | 249 | Chemie (HOH) |
Sequence modifications
A: 696 - 1040 (UniProt: Q6PJP8)
| PDB | External Database | Details |
|---|---|---|
| Met 697 | Arg 697 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39140.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 384.5 | |
| All* | Total formula weight | 39524.8 |
