8CEW

Crystal structure of human DNA cross-link repair 1A in complex with N-hydroxyimide inhibitor H1

Summary for 8CEW

Entry DOI	10.2210/pdb8cew/pdb
Descriptor	DNA cross-link repair 1A protein, DIMETHYL SULFOXIDE, NICKEL (II) ION, ... (6 entities in total)
Functional Keywords	snm1a, nuclease inhibition, icl, hydrolase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	39829.00
Authors	Newman, J.A.,Yosaatmadja, Y.,Baddock, H.T.,Bielinski, M.,von Delft, F.,Bountra, C.,McHugh, P.J.,Schofield, C.J.,Gileadi, O. (deposition date: 2023-02-02, release date: 2024-02-21)
Primary citation	Newman, J.A.,Yosaatmadja, Y.,Baddock, H.T.,Bielinski, M.,von Delft, F.,Bountra, C.,McHugh, P.J.,Schofield, C.J.,Gileadi, O. Crystal structure of human DNA cross-link repair 1A in complex with N-hydroxyimide inhibitor H1 To Be Published,
Experimental method	X-RAY DIFFRACTION (1.53 Å)

Structure validation