2J95
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2j95 by Molmil](/molmil-images/mine/2j95) | CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX | 分子名称: | 5'-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-2,2'-BITHIOPHENE-5-SULFONAMIDE, ACTIVATED FACTOR XA HEAVY CHAIN, ACTIVATED FACTOR XA LIGHT CHAIN, ... | 著者 | Chan, C, Borthwick, A.D, Brown, D, Campbell, M, Chaudry, L, Chung, C.W, Convery, M.A, Hamblin, J.N, Johnstone, L, Kelly, H.A, Kleanthous, S, Burns-Kurtis, C.L, Patikis, A, Patel, C, Pateman, A.J, Senger, S, Shah, G.P, Toomey, J.R, Watson, N.S, Weston, H.E, Whitworth, C, Young, R.J, Zhou, P. | 登録日 | 2006-11-02 | 公開日 | 2007-03-20 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Factor Xa Inhibitors: S1 Binding Interactions of a Series of N-{(3S)-1-[(1S)-1-Methyl-2-Morpholin-4-Yl-2-Oxoethyl]-2-Oxopyrrolidin-3-Yl}Sulfonamides. J.Med.Chem., 50, 2007
|
|
6PK8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pk8 by Molmil](/molmil-images/mine/6pk8) | Antibody scFv-M204 dimeric state | 分子名称: | SULFATE ION, scFv-M204 antibody | 著者 | Abskharon, R, Sawaya, M.R, Seidler, P.M, Cascio, D, Eisenberg, D.S. | 登録日 | 2019-06-28 | 公開日 | 2020-06-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease. J.Biol.Chem., 295, 2020
|
|
2KKQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kkq by Molmil](/molmil-images/mine/2kkq) | Solution NMR Structure of the Ig-like C2-type 2 Domain of Human Myotilin. Northeast Structural Genomics Target HR3158. | 分子名称: | Myotilin | 著者 | Rossi, P, Shastry, R, Ciccosanti, C, Hamilton, K, Xiao, R, Acton, T.B, Swapna, G.V.T, Nair, R, Everett, J.K, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-06-29 | 公開日 | 2009-07-07 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of the Ig-like C2-type 2 Domain of Human Myotilin. Northeast Structural Genomics Target HR3158. To be Published
|
|
2JXY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jxy by Molmil](/molmil-images/mine/2jxy) | Solution structure of the hemopexin-like domain of MMP12 | 分子名称: | CALCIUM ION, Macrophage metalloelastase | 著者 | Bertini, I, Calderone, V, Fragai, M, Jaiswal, R, Luchinat, C, Melikian, M. | 登録日 | 2007-12-01 | 公開日 | 2008-05-27 | 最終更新日 | 2022-03-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Evidence of reciprocal reorientation of the catalytic and hemopexin-like domains of full-length MMP-12 J.Am.Chem.Soc., 130, 2008
|
|
6PSC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6psc by Molmil](/molmil-images/mine/6psc) | Antibody scFv-M204 trimeric state | 分子名称: | scFv-M204 antibody | 著者 | Abskharon, R, Sawaya, M.R, Seidler, P.M, Cascio, D, Eisenberg, D.S. | 登録日 | 2019-07-12 | 公開日 | 2020-06-17 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease. J.Biol.Chem., 295, 2020
|
|
2KKA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2kka by Molmil](/molmil-images/mine/2kka) | Human telomere DNA two-tetrad quadruplex structure in K+ solution | 分子名称: | 5'-D(*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*IP*GP*GP*TP*TP*AP*GP*GP*GP*T)-3' | 著者 | Zhang, Z, Dai, J, Yang, D. | 登録日 | 2009-06-16 | 公開日 | 2009-12-15 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of a two-G-tetrad intramolecular G-quadruplex formed by a variant human telomeric sequence in K+ solution: insights into the interconversion of human telomeric G-quadruplex structures. Nucleic Acids Res., 38, 2010
|
|
6NY0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ny0 by Molmil](/molmil-images/mine/6ny0) | |
2K9C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2k9c by Molmil](/molmil-images/mine/2k9c) | Paramagnetic shifts in solid-state NMR of Proteins to elicit structural information | 分子名称: | COBALT (II) ION, Macrophage metalloelastase | 著者 | Balayssac, S, Bertini, I, Bhaumik, A, Lelli, M, Luchinat, C. | 登録日 | 2008-10-08 | 公開日 | 2008-11-18 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Paramagnetic shifts in solid-state NMR of proteins to elicit structural information Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
2KNF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2knf by Molmil](/molmil-images/mine/2knf) | Solution structure and functional characterization of human plasminogen kringle 5 | 分子名称: | Plasminogen | 著者 | Battistel, M.D, Grishaev, A, An, S.A, Castellino, F.J, Llinas, M. | 登録日 | 2009-08-21 | 公開日 | 2009-10-27 | 最終更新日 | 2021-10-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and functional characterization of human plasminogen kringle 5. Biochemistry, 48, 2009
|
|
6NIW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6niw by Molmil](/molmil-images/mine/6niw) | Crystal structure of P[6] rotavirus | 分子名称: | DI(HYDROXYETHYL)ETHER, Protease-sensitive outer capsid protein | 著者 | Xu, S, Liu, Y, Lakamp, L, Ahmed, L, Jiang, X, Kennedy, M.A. | 登録日 | 2019-01-01 | 公開日 | 2020-01-08 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Molecular basis of P[II] major human rotavirus VP8* domain recognition of histo-blood group antigens. Plos Pathog., 16, 2020
|
|
2NU4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2nu4 by Molmil](/molmil-images/mine/2nu4) | Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I | 分子名称: | Ovomucoid, Streptogrisin B, Proteinase B | 著者 | Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G. | 登録日 | 2006-11-08 | 公開日 | 2006-11-21 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I To be Published
|
|
6N8B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n8b by Molmil](/molmil-images/mine/6n8b) | Crystal structure of transcription regulator AcaB from uropathogenic E. coli | 分子名称: | CALCIUM ION, transcription regulator AcaB | 著者 | Luo, Z, Hancock, S.J, Schembri, M.A, Kobe, B. | 登録日 | 2018-11-29 | 公開日 | 2020-07-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | 主引用文献 | Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB. Nat Microbiol, 5, 2020
|
|
6N64
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n64 by Molmil](/molmil-images/mine/6n64) | Crystal structure of mouse SMCHD1 hinge domain | 分子名称: | Structural maintenance of chromosomes flexible hinge domain-containing protein 1, Uncharacterized peptide from Structural maintenance of chromosomes flexible hinge domain-containing protein 1 | 著者 | Birkinshaw, R.W, Chen, K, Czabotar, P.E, Blewitt, M.E, Murphy, J.M. | 登録日 | 2018-11-25 | 公開日 | 2020-06-17 | 最終更新日 | 2021-01-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal structure of the hinge domain of Smchd1 reveals its dimerization mode and nucleic acid-binding residues. Sci.Signal., 13, 2020
|
|
6N8A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n8a by Molmil](/molmil-images/mine/6n8a) | Crystal structure of selenomethionine-containing AcaB from uropathogenic E. coli | 分子名称: | CHLORIDE ION, transcription regulator AcaB | 著者 | Luo, Z, Hancock, S.J, Schembri, M.A, Kobe, B. | 登録日 | 2018-11-28 | 公開日 | 2020-07-15 | 最終更新日 | 2021-01-27 | 実験手法 | X-RAY DIFFRACTION (3.4011 Å) | 主引用文献 | Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB. Nat Microbiol, 5, 2020
|
|
2NU3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2nu3 by Molmil](/molmil-images/mine/2nu3) | Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I | 分子名称: | Ovomucoid, Streptogrisin B, Proteinase B | 著者 | Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Huang, K, Laskowski Jr, M, James, M.N.G. | 登録日 | 2006-11-08 | 公開日 | 2006-11-21 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I To be Published
|
|
6OEO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6oeo by Molmil](/molmil-images/mine/6oeo) | Cryo-EM structure of mouse RAG1/2 NFC complex (DNA1) | 分子名称: | CALCIUM ION, DNA (46-MER), DNA (57-MER), ... | 著者 | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | 登録日 | 2019-03-27 | 公開日 | 2020-01-29 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.69 Å) | 主引用文献 | Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
|
|
6OAI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6oai by Molmil](/molmil-images/mine/6oai) | Crystal structure of P[6] rotavirus vp8* complexed with LNFPI | 分子名称: | Protease-sensitive outer capsid protein, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | 著者 | Xu, S, Liu, Y, Jiang, X, Kennedy, M.A. | 登録日 | 2019-03-16 | 公開日 | 2020-03-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular basis of P[II] major human rotavirus VP8* domain recognition of histo-blood group antigens. Plos Pathog., 16, 2020
|
|
6OAN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6oan by Molmil](/molmil-images/mine/6oan) | |
6OEQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6oeq by Molmil](/molmil-images/mine/6oeq) | Cryo-EM structure of mouse RAG1/2 12RSS-PRC/23RSS-NFC complex (DNA1) | 分子名称: | CALCIUM ION, DNA (46-MER), DNA (57-MER), ... | 著者 | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | 登録日 | 2019-03-27 | 公開日 | 2020-01-29 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
|
|
6QRI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qri by Molmil](/molmil-images/mine/6qri) | Structure of rabbit G-actin in complex with chivosazole A | 分子名称: | (2~{R},3~{R},5~{S},6~{E},8~{E},10~{Z},12~{S},13~{R},16~{Z},18~{E},20~{Z},22~{E},24~{R},25~{S},26~{E},28~{Z})-13-[(2~{S},3~{S},5~{S})-3,5-bis(oxidanyl)hexan-2-yl]-25-[(2~{R},3~{R},4~{S},5~{R},6~{R})-3,4-dimethoxy-6-methyl-5-oxidanyl-oxan-2-yl]oxy-3-methoxy-2,12,22,24-tetramethyl-5-oxidanyl-14,32-dioxa-33-azabicyclo[28.2.1]tritriaconta-1(33),6,8,10,16,18,20,22,26,28,30-undecaen-15-one, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | 著者 | Schneider, S, Wang, S, Zahler, S. | 登録日 | 2019-02-19 | 公開日 | 2019-07-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Chivosazole A Modulates Protein-Protein Interactions of Actin. J.Nat.Prod., 82, 2019
|
|
6OER
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6oer by Molmil](/molmil-images/mine/6oer) | Cryo-EM structure of mouse RAG1/2 NFC complex (DNA2) | 分子名称: | CALCIUM ION, DNA (46-MER), DNA (57-MER), ... | 著者 | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | 登録日 | 2019-03-27 | 公開日 | 2020-01-29 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | 主引用文献 | Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
|
|
6QM8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qm8 by Molmil](/molmil-images/mine/6qm8) | |
6QM7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6qm7 by Molmil](/molmil-images/mine/6qm7) | |
6NAN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nan by Molmil](/molmil-images/mine/6nan) | NMR structure determination of Ixolaris and Factor X interaction reveals a noncanonical mechanism of Kunitz inhibition | 分子名称: | Ixolaris | 著者 | De Paula, V.S, Sgourakis, N.G, Francischetti, I.M.B, Almeida, F.C.L, Monteiro, R.Q, Valente, A.P. | 登録日 | 2018-12-06 | 公開日 | 2019-06-12 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure determination of Ixolaris and factor X(a) interaction reveals a noncanonical mechanism of Kunitz inhibition. Blood, 134, 2019
|
|
2NU2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2nu2 by Molmil](/molmil-images/mine/2nu2) | Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I | 分子名称: | Ovomucoid, Streptogrisin B, Protease B | 著者 | Bateman, K.S, Anderson, S, Lu, W, Qasim, M.A, Laskowski Jr, M, James, M.N.G. | 登録日 | 2006-11-08 | 公開日 | 2006-11-21 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Accommodation of positively-charged residues in a hydrophobic specificity pocket: Crystal structures of SGPB in complex with OMTKY3 variants Lys18I and Arg18I To be Published
|
|