6N64

Crystal structure of mouse SMCHD1 hinge domain

Summary for 6N64

Entry DOI	10.2210/pdb6n64/pdb
Related	1GXJ 1GXK 2WD5 4PUP 5MG8
Descriptor	Structural maintenance of chromosomes flexible hinge domain-containing protein 1, Uncharacterized peptide from Structural maintenance of chromosomes flexible hinge domain-containing protein 1 (2 entities in total)
Functional Keywords	smchd1 epigenetic control dna binding smc protein, dna binding protein
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	8
Total formula weight	155940.48
Authors	Birkinshaw, R.W.,Chen, K.,Czabotar, P.E.,Blewitt, M.E.,Murphy, J.M. (deposition date: 2018-11-25, release date: 2020-06-17, Last modification date: 2021-01-20)
Primary citation	Chen, K.,Birkinshaw, R.W.,Gurzau, A.D.,Wanigasuriya, I.,Wang, R.,Iminitoff, M.,Sandow, J.J.,Young, S.N.,Hennessy, P.J.,Willson, T.A.,Heckmann, D.A.,Webb, A.I.,Blewitt, M.E.,Czabotar, P.E.,Murphy, J.M. Crystal structure of the hinge domain of Smchd1 reveals its dimerization mode and nucleic acid-binding residues. Sci.Signal., 13:-, 2020 Cited by PubMed: 32546545 DOI: 10.1126/scisignal.aaz5599 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation