4L5W
 
 | | Structural implications of the secondary CO2 binding pocket in human carbonic anhydrase II | | 分子名称: | Carbonic anhydrase 2, GLYCEROL, ZINC ION | | 著者 | Boone, C.D, Gill, S, McKenna, R. | | 登録日 | 2013-06-11 | | 公開日 | 2014-04-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural, catalytic and stabilizing consequences of aromatic cluster variants in human carbonic anhydrase II.
Arch.Biochem.Biophys., 539, 2013
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3U8D
 | | Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism | | 分子名称: | (3-{[3-(2-amino-2-oxoethyl)-1-benzyl-2-ethyl-1H-indol-5-yl]oxy}propyl)phosphonic acid, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Lee, L.K, Bryant, K.J, Bouveret, R, Lei, P.-W, Duff, A.P, Harrop, S.J, Huang, E.P, Harvey, R.P, Gelb, M.H, Gray, P.P, Curmi, P.M, Cunningham, A.M, Church, W.B, Scott, K.F. | | 登録日 | 2011-10-16 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.805 Å) | | 主引用文献 | Selective Inhibition of Human Group IIA-secreted Phospholipase A2 (hGIIA) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of hGIIA to Vimentin in Rheumatoid Synoviocytes.
J.Biol.Chem., 288, 2013
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2E9Z
 | | Foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA, ATP and UTP | | 分子名称: | 5'-R(*CP*AP*UP*GP*GP*GP*CP*CP*C)-3', 5'-R(*GP*GP*GP*CP*CP*CP*A)-3', MAGNESIUM ION, ... | | 著者 | Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. | | 登録日 | 2007-01-29 | | 公開日 | 2007-06-26 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Sequential structures provide insights into the fidelity of RNA replication
Proc.Natl.Acad.Sci.Usa, 104, 2007
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3JRA
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3UCT
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1RZB
 | | X-RAY ANALYSIS OF METAL SUBSTITUTED HUMAN CARBONIC ANHYDRASE II DERIVATIVES | | 分子名称: | CARBONIC ANHYDRASE II, COBALT (II) ION, SULFATE ION | | 著者 | Hakansson, K, Wehnert, A, Liljas, A. | | 登録日 | 1993-05-25 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | X-ray analysis of metal-substituted human carbonic anhydrase II derivatives.
Acta Crystallogr.,Sect.D, 50, 1994
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3RGE
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2A66
 | | Human Liver Receptor Homologue DNA-Binding Domain (hLRH-1 DBD) in Complex with dsDNA from the hCYP7A1 Promoter | | 分子名称: | 5'-D(*CP*TP*GP*GP*CP*CP*TP*TP*GP*AP*AP*C)-3', 5'-D(*GP*TP*TP*CP*AP*AP*GP*GP*CP*CP*AP*G)-3', ACETATE ION, ... | | 著者 | Solomon, I.H, Hager, J.M, Safi, R, McDonnell, D.P, Redinbo, M.R, Ortlund, E.A. | | 登録日 | 2005-07-01 | | 公開日 | 2005-12-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of the Human LRH-1 DBD-DNA Complex Reveals Ftz-F1 Domain Positioning is Required for Receptor Activity.
J.Mol.Biol., 354, 2005
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2A5Y
 | | Structure of a CED-4/CED-9 complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Apoptosis regulator ced-9, MAGNESIUM ION, ... | | 著者 | Yan, N, Liu, Q, Hao, Q, Gu, L, Shi, Y. | | 登録日 | 2005-07-01 | | 公開日 | 2005-10-11 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans.
Nature, 437, 2005
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4C3H
 | | Structure of 14-subunit RNA polymerase I at 3.27 A resolution, crystal form C2-93 | | 分子名称: | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14, ... | | 著者 | Fernandez-Tornero, C, Moreno-Morcillo, M, Rashid, U.J, Taylor, N.M.I, Ruiz, F.M, Gruene, T, Legrand, P, Steuerwald, U, Muller, C.W. | | 登録日 | 2013-08-24 | | 公開日 | 2013-10-23 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.27 Å) | | 主引用文献 | Crystal Structure of the 14-Subunit RNA Polymerase I
Nature, 502, 2013
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1S6O
 | | Solution structure and backbone dynamics of the apo-form of the second metal-binding domain of the Menkes protein ATP7A | | 分子名称: | Copper-transporting ATPase 1 | | 著者 | Banci, L, Bertini, I, Del Conte, R, D'Onofrio, M, Rosato, A, Structural Proteomics in Europe (SPINE) | | 登録日 | 2004-01-26 | | 公開日 | 2004-04-06 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure and Backbone Dynamics of the Cu(I) and Apo Forms of the Second Metal-Binding Domain of the Menkes Protein ATP7A.
Biochemistry, 43, 2004
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1KV3
 | | HUMAN TISSUE TRANSGLUTAMINASE IN GDP BOUND FORM | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Protein-glutamine gamma-glutamyltransferase | | 著者 | Liu, S, Cerione, R.A, Clardy, J. | | 登録日 | 2002-01-24 | | 公開日 | 2002-03-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for the guanine nucleotide-binding activity of tissue transglutaminase and its regulation of transamidation activity.
Proc.Natl.Acad.Sci.USA, 99, 2002
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2ABE
 | | Carbonic anhydrase activators: X-ray crystal structure of the adduct of human isozyme II with L-histidine as a platform for the design of stronger activators | | 分子名称: | Carbonic anhydrase II, HISTIDINE, MERCURY (II) ION, ... | | 著者 | Temperini, C, Scozzafava, A, Puccetti, L, Supuran, C.T. | | 登録日 | 2005-07-15 | | 公開日 | 2005-10-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Carbonic anhydrase activators: X-ray crystal structure of the adduct of human isozyme II with l-histidine as a platform for the design of stronger activators.
Bioorg.Med.Chem.Lett., 15, 2005
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1SKA
 | | Crystallographic snapshots of Aspergillus fumigatus phytase revealing its enzymatic dynamics | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-phytase A | | 著者 | Liu, Q, Huang, Q, Lei, X.G, Hao, Q. | | 登録日 | 2004-03-04 | | 公開日 | 2004-09-28 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Crystallographic Snapshots of Aspergillus fumigatus Phytase, Revealing Its Enzymatic Dynamics
Structure, 12, 2004
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1KXK
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3K0J
 | | Crystal structure of the E. coli ThiM riboswitch in complex with thiamine pyrophosphate and the U1A crystallization module | | 分子名称: | MAGNESIUM ION, RNA (87-MER), THIAMINE DIPHOSPHATE, ... | | 著者 | Kulshina, N, Edwards, T.E, Ferre-D'Amare, A.R. | | 登録日 | 2009-09-24 | | 公開日 | 2009-12-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Thermodynamic analysis of ligand binding and ligand binding-induced tertiary structure formation by the thiamine pyrophosphate riboswitch.
Rna, 16, 2010
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2ABM
 | | Crystal Structure of Aquaporin Z Tetramer Reveals both Open and Closed Water-conducting Channels | | 分子名称: | (1S)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PENTANOYLOXY)METHYL]ETHYL OCTANOATE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-O-octyl-beta-D-glucopyranose, ... | | 著者 | Jiang, J, Daniels, B.V, Fu, D. | | 登録日 | 2005-07-15 | | 公開日 | 2005-09-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal Structure of AqpZ Tetramer Reveals Two Distinct Arg-189 Conformations Associated with Water Permeation through the Narrowest Constriction of the Water-conducting Channel.
J.Biol.Chem., 281, 2006
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3Q76
 | | Structure of human neutrophil elastase (uncomplexed) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Neutrophil elastase, ... | | 著者 | Hansen, G, Niefind, K. | | 登録日 | 2011-01-04 | | 公開日 | 2011-05-11 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.861 Å) | | 主引用文献 | Unexpected active-site flexibility in the structure of human neutrophil elastase in complex with a new dihydropyrimidone inhibitor.
J.Mol.Biol., 409, 2011
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4HXI
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1SOF
 | | Crystal structure of the azotobacter vinelandii bacterioferritin at 2.6 A resolution | | 分子名称: | BARIUM ION, Bacterioferritin, FE (II) ION, ... | | 著者 | Liu, H.L, Huang, J.F, Bi, R.C. | | 登録日 | 2004-03-14 | | 公開日 | 2005-04-05 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | 2.6 A resolution crystal structure of the bacterioferritin from Azotobacter vinelandii
Febs Lett., 573, 2004
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1RZC
 | | X-RAY ANALYSIS OF METAL SUBSTITUTED HUMAN CARBONIC ANHYDRASE II DERIVATIVES | | 分子名称: | CARBONIC ANHYDRASE II, COPPER (II) ION, OXYGEN MOLECULE | | 著者 | Hakansson, K, Wehnert, A, Liljas, A. | | 登録日 | 1993-05-25 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-ray analysis of metal-substituted human carbonic anhydrase II derivatives.
Acta Crystallogr.,Sect.D, 50, 1994
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3UCW
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4I9X
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3WK5
 | | Crystal structure of soluble epoxide hydrolase in complex with fragment inhibitor | | 分子名称: | 2-cyclopentyl-N-(1,3-thiazol-2-yl)acetamide, Bifunctional epoxide hydrolase 2, MAGNESIUM ION, ... | | 著者 | Amano, Y, Yamaguchi, T, Tanabe, E. | | 登録日 | 2013-10-17 | | 公開日 | 2014-04-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | | 主引用文献 | Structural insights into binding of inhibitors to soluble epoxide hydrolase gained by fragment screening and X-ray crystallography.
Bioorg.Med.Chem., 22, 2014
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3JRC
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