6DMU

PI(4,5)P2 bound full-length rbTRPV5

Summary for 6DMU

Entry DOI	10.2210/pdb6dmu/pdb
EMDB information	7966
Descriptor	Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate (2 entities in total)
Functional Keywords	pi(4, 5)p2, trpv5, full-length, ion channel, transport protein
Biological source	Oryctolagus cuniculus (Rabbit)
Total number of polymer chains	4
Total formula weight	334584.89
Authors	Hughes, T.E.T.,Pumroy, R.A.,Moiseenkova-Bell, V.Y. (deposition date: 2018-06-05, release date: 2018-10-24, Last modification date: 2024-03-13)
Primary citation	Hughes, T.E.T.,Pumroy, R.A.,Yazici, A.T.,Kasimova, M.A.,Fluck, E.C.,Huynh, K.W.,Samanta, A.,Molugu, S.K.,Zhou, Z.H.,Carnevale, V.,Rohacs, T.,Moiseenkova-Bell, V.Y. Structural insights on TRPV5 gating by endogenous modulators. Nat Commun, 9:4198-4198, 2018 Cited by PubMed: 30305626 DOI: 10.1038/s41467-018-06753-6 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4 Å)

Structure validation