4R5B

Human Carbonic Anhydrase II in Complex with a Carbohydrate-Based Sulfamate

Summary for 4R5B

Entry DOI	10.2210/pdb4r5b/pdb
Related	4R59 4R5A
Descriptor	Carbonic anhydrase 2, ZINC ION, GLYCEROL, ... (5 entities in total)
Functional Keywords	cytosol, lyase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	29838.97
Authors	Mahon, B.P.,McKenna, R. (deposition date: 2014-08-20, release date: 2014-10-15, Last modification date: 2023-09-20)
Primary citation	Moeker, J.,Mahon, B.P.,Bornaghi, L.F.,Vullo, D.,Supuran, C.T.,McKenna, R.,Poulsen, S.A. Structural Insights into Carbonic Anhydrase IX Isoform Specificity of Carbohydrate-Based Sulfamates. J.Med.Chem., 57:8635-8645, 2014 Cited by PubMed: 25254302 DOI: 10.1021/jm5012935 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation