1G4U

CRYSTAL STRUCTURE OF THE SALMONELLA TYROSINE PHOSPHATASE AND GTPASE ACTIVATING PROTEIN SPTP BOUND TO RAC1

Summary for 1G4U

• Entry DOI: 10.2210/pdb1g4u/pdb
• Related: 1G4W
• NMR Information: BMRB: 5511
• Descriptor: PROTEIN TYROSINE PHOSPHATASE SPTP, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: virulence factor, gap, tyrosine phosphatase, 4-helix bundle, gtpase, signaling protein
• Biological source: Salmonella typhimurium; More
• Cellular location: Secreted : P74873; Cell membrane ; Lipid-anchor ; Cytoplasmic side : P63000
• Total number of polymer chains: 2
• Total formula weight: 63081.93

Authors

Stebbins, C.E.,Galan, J.E. (deposition date: 2000-10-28, release date: 2001-01-24, Last modification date: 2024-02-07)

• Primary citation: Stebbins, C.E.,Galan, J.E.; Modulation of host signaling by a bacterial mimic: structure of the Salmonella effector SptP bound to Rac1.; Mol.Cell, 6:1449-1460, 2000; PubMed: 11163217; DOI: 10.1016/S1097-2765(00)00141-6

Experimental method

X-RAY DIFFRACTION (2.3 Å)