1G4U
CRYSTAL STRUCTURE OF THE SALMONELLA TYROSINE PHOSPHATASE AND GTPASE ACTIVATING PROTEIN SPTP BOUND TO RAC1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (S) | PROTEIN TYROSINE PHOSPHATASE SPTP | polymer | 383 | 42127.8 | 1 | UniProt (P74873) Pfam (PF03545) Pfam (PF00102) | Salmonella typhimurium | |
| 2 | B (R) | RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 | polymer | 184 | 20402.7 | 1 | UniProt (P63000) Pfam (PF00071) | Homo sapiens (human) | |
| 3 | C (R) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 4 | D (R) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 5 | E (R) | ALUMINUM FLUORIDE | non-polymer | 84.0 | 1 | Chemie (AF3) PubChem (2124) | |||
| 6 | F, G (S, R) | water | water | 18.0 | 334 | Chemie (HOH) |
Sequence modifications
R: 1 - 184 (UniProt: P63000)
| PDB | External Database | Details |
|---|---|---|
| Ser 78 | Phe 78 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62530.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 551.5 | |
| All* | Total formula weight | 63081.9 |






