7NZW

Crystal structure of chimeric carbonic anhydrase VA with 4-[(4,6-dimethylpyrimidin-2-yl)thio]-2,3,5,6-tetrafluorobenzenesulfonamide

Summary for 7NZW

• Entry DOI: 10.2210/pdb7nzw/pdb
• Related: 7NZR 7NZS 7NZT 7NZU
• Descriptor: Carbonic anhydrase 2, ZINC ION, 4-[(4,6-dimethylpyrimidin-2-yl)thio]-2,3,5,6-tetrafluorobenzenesulfonamide, ... (6 entities in total)
• Functional Keywords: drug design, carbonic anhydrase, benzenesulfonamide, metal-binding, lyase-lyase inhibitor complex, lyase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 29911.03

Authors

Smirnov, A.,Manakova, E.,Grazulis, S. (deposition date: 2021-03-24, release date: 2022-04-13, Last modification date: 2024-01-31)

• Primary citation: Smirnov, A.; Crystal structure of chimeric carbonic anhydrase VA; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.45 Å)