1G4J
CARBONIC ANHYDRASE II (F131V) COMPLEXED WITH 4-(AMINOSULFONYL)-N-[(2,3,4,5,6-PENTAFLUOROPHENYL)METHYL]-BENZAMIDE
Summary for 1G4J
Entry DOI | 10.2210/pdb1g4j/pdb |
Related | 1g1d 1g3z 1g45 1g46 1g48 |
Descriptor | CARBONIC ANHYDRASE II, ZINC ION, MERCURY (II) ION, ... (5 entities in total) |
Functional Keywords | carbonic anhydrase ii, f131v, 4-(aminosulfonyl)-n-[(2, 3, 4, 5, 6-pentafluorophenyl)methyl]-benzamide, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 30136.40 |
Authors | Kim, C.-Y.,Chang, J.S.,Doyon, J.B.,Baird Jr., T.T.,Fierke, C.A.,Jain, A.,Christianson, D.W. (deposition date: 2000-10-27, release date: 2000-11-08, Last modification date: 2024-02-07) |
Primary citation | Kim, C.-Y.,Chang, J.S.,Doyon, J.B.,Baird Jr., T.T.,Fierke, C.A.,Jain, A.,Christianson, D.W. Contribution of Flourine to Protein-ligand Affinity in the Binding of Flouroaromatic Inhibitors to Carbonic Anhydrase II J.Am.Chem.Soc., 122:12125-12134, 2000 Cited by DOI: 10.1021/ja002627nPDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.84 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)